Bismuth intoxication resulting in acute kidney injury in a pregnant adolescent girl
Bismuth intoxication is a rare cause of acute kidney injury (AKI) and is usually reversible by appropriate therapeutic measures. We present here a case of an adolescent pregnant girl who developed AKI due to an overdose of colloidal bismuth subcitrate (CBS, total amount of 6 g). She received parent...
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| Language: | English |
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Hacettepe University Institute of Child Health
2019-04-01
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| Series: | The Turkish Journal of Pediatrics |
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| Online Access: | https://turkjpediatr.org/article/view/691 |
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| author | Aslı Çelebi-Tayfur Raziye Merve Yaradılmış Fatma Ulus Aysun Çaltık-Yılmaz Esra Özayar Berrin Koşar Bahar Büyükkaragöz Eyüp Horasanlı |
| author_facet | Aslı Çelebi-Tayfur Raziye Merve Yaradılmış Fatma Ulus Aysun Çaltık-Yılmaz Esra Özayar Berrin Koşar Bahar Büyükkaragöz Eyüp Horasanlı |
| author_sort | Aslı Çelebi-Tayfur |
| collection | DOAJ |
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Bismuth intoxication is a rare cause of acute kidney injury (AKI) and is usually reversible by appropriate therapeutic measures. We present here a case of an adolescent pregnant girl who developed AKI due to an overdose of colloidal bismuth subcitrate (CBS, total amount of 6 g). She received parenteral chelating agent dimercaprol for 14 days. Continuous venovenous hemodiafiltration (CVVHD) with high-flux membrane was carried out in the first 3 days of chelating therapy and intermittent hemodialysis for 11 days, thereafter. The patient recovered clinically and was discharged after 21 days. She gave birth to a healthy term boy. At the last visit, the baby was 6 months old with normal growth and development as well as normal kidney functions. Neither deterioration in renal functions nor emergence of proteinuria was recorded in the patient during follow-up care after hospital discharge. In cases of AKI due to an overdose of CBS, treatment with dimercaprol combined with high flux hemodiafiltration and subsequently hemodialysis appears to be both useful and safe for bismuth elimination.
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| format | Article |
| id | doaj-art-cbe175a59f8b40acb9a91084e20eb63c |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2019-04-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-cbe175a59f8b40acb9a91084e20eb63c2025-08-20T03:16:22ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212019-04-0161210.24953/turkjped.2019.02.024Bismuth intoxication resulting in acute kidney injury in a pregnant adolescent girlAslı Çelebi-Tayfur0Raziye Merve Yaradılmış1Fatma Ulus2Aysun Çaltık-Yılmaz3Esra Özayar4Berrin Koşar5Bahar Büyükkaragöz6Eyüp Horasanlı7Departments of Pediatric Nephrology, Keçiören Training and Research Hospital, University of Health Sciences, Ankara, Turkey.Departments of Pediatrics, Keçiören Training and Research Hospital, University of Health Sciences, Ankara, Turkey.Departments of Anesthesiology and Reanimation, Keçiören Training and Research Hospital, University of Health Sciences, Ankara, Turkey.Departments of Pediatric Nephrology, Keçiören Training and Research Hospital, University of Health Sciences, Ankara, Turkey.Departments of Anesthesiology and Reanimation, Keçiören Training and Research Hospital, University of Health Sciences, Ankara, Turkey.Departments of Anesthesiology and Reanimation, Keçiören Training and Research Hospital, University of Health Sciences, Ankara, Turkey.Departments of Pediatric Nephrology, Keçiören Training and Research Hospital, University of Health Sciences, Ankara, Turkey.Departments of Anesthesiology and Reanimation, Keçiören Training and Research Hospital, University of Health Sciences, Ankara, Turkey. Bismuth intoxication is a rare cause of acute kidney injury (AKI) and is usually reversible by appropriate therapeutic measures. We present here a case of an adolescent pregnant girl who developed AKI due to an overdose of colloidal bismuth subcitrate (CBS, total amount of 6 g). She received parenteral chelating agent dimercaprol for 14 days. Continuous venovenous hemodiafiltration (CVVHD) with high-flux membrane was carried out in the first 3 days of chelating therapy and intermittent hemodialysis for 11 days, thereafter. The patient recovered clinically and was discharged after 21 days. She gave birth to a healthy term boy. At the last visit, the baby was 6 months old with normal growth and development as well as normal kidney functions. Neither deterioration in renal functions nor emergence of proteinuria was recorded in the patient during follow-up care after hospital discharge. In cases of AKI due to an overdose of CBS, treatment with dimercaprol combined with high flux hemodiafiltration and subsequently hemodialysis appears to be both useful and safe for bismuth elimination. https://turkjpediatr.org/article/view/691acute kidney injurybismuth intoxicationdimercaprolteratogenicity |
| spellingShingle | Aslı Çelebi-Tayfur Raziye Merve Yaradılmış Fatma Ulus Aysun Çaltık-Yılmaz Esra Özayar Berrin Koşar Bahar Büyükkaragöz Eyüp Horasanlı Bismuth intoxication resulting in acute kidney injury in a pregnant adolescent girl The Turkish Journal of Pediatrics acute kidney injury bismuth intoxication dimercaprol teratogenicity |
| title | Bismuth intoxication resulting in acute kidney injury in a pregnant adolescent girl |
| title_full | Bismuth intoxication resulting in acute kidney injury in a pregnant adolescent girl |
| title_fullStr | Bismuth intoxication resulting in acute kidney injury in a pregnant adolescent girl |
| title_full_unstemmed | Bismuth intoxication resulting in acute kidney injury in a pregnant adolescent girl |
| title_short | Bismuth intoxication resulting in acute kidney injury in a pregnant adolescent girl |
| title_sort | bismuth intoxication resulting in acute kidney injury in a pregnant adolescent girl |
| topic | acute kidney injury bismuth intoxication dimercaprol teratogenicity |
| url | https://turkjpediatr.org/article/view/691 |
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