Cytological Profile of Solid and Cystic Lesions Arising from Various Sites in the Body: A Cross-sectional Study
Introduction: Fine Needle Aspiration Cytology (FNAC) is a minimally invasive, cost-effective, and efficient technique for obtaining diagnostic cellular material with minimal discomfort and a low patient complication rate. Aim: To study various solid and cystic lesions in the body using FNAC, follow...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2025-05-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/20941/74734_CE[Ra1]_F(SHU)_QC(PS_SS)_PF1(VD_IS)_PFA(IS)_PB(VD_IS)_PN(IS).pdf |
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| Summary: | Introduction: Fine Needle Aspiration Cytology (FNAC) is a minimally invasive, cost-effective, and efficient technique for obtaining diagnostic cellular material with minimal discomfort and a low patient complication rate.
Aim: To study various solid and cystic lesions in the body using FNAC, followed by histopathological examination for definitive diagnosis.
Materials and Methods: The present cross-sectional Study was conducted on 383 patients who underwent surgery for cystic and solid lesions in the Department of Pathology at Chengalpattu Medical College, Chengalpattu, Tamil Nadu, India. over a period of one year from June 2022 to June 2023. Patients with various solid lesions (breast, thyroid, salivary gland lesions, lymphoma, etc.) and cystic lesions (epidermal cysts, ganglionic cysts, fibro-cystic breast disease, etc.) referred for cytopathological analysis were included. FNAC results were tabulated, and histopathological examination of surgically removed tissues was performed for definitive diagnosis.
Results: The study shows that FNAC is useful for diagnosing solid and cystic lesions, with a concordance rate of 83.66% for solid lesions and 90.90% for cystic lesions when compared to histopathology. However, it also highlights difficulties in distinguishing between benign and malignant thyroid and breast lesions, emphasising the need for further testing in uncertain cases.
Conclusion: The FNAC is a simple, non traumatic, safe, cost-effective outpatient procedure. It provides high diagnostic accuracy for many conditions related to both solid and cystic lesions, especially when combined with imaging guidance and expert cytological interpretation. |
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| ISSN: | 2249-782X 0973-709X |