A rim-enhanced mass with central cystic changes on MR imaging: how to distinguish breast cancer from inflammatory breast diseases?
<h4>Objective</h4>To evaluate the capacity of magnetic resonance imaging (MRI) to distinguish breast cancer from inflammatory breast diseases manifesting as a rim-enhanced mass with central cystic changes.<h4>Materials and methods</h4>Forty cases of breast cancer and 52 of in...
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Public Library of Science (PLoS)
2014-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090355&type=printable |
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| author | Lijun Wang Dengbin Wang Xiaochun Fei Mei Ruan Weimin Chai Lin Xu Xiaoxiao Li |
| author_facet | Lijun Wang Dengbin Wang Xiaochun Fei Mei Ruan Weimin Chai Lin Xu Xiaoxiao Li |
| author_sort | Lijun Wang |
| collection | DOAJ |
| description | <h4>Objective</h4>To evaluate the capacity of magnetic resonance imaging (MRI) to distinguish breast cancer from inflammatory breast diseases manifesting as a rim-enhanced mass with central cystic changes.<h4>Materials and methods</h4>Forty cases of breast cancer and 52 of inflammatory breast diseases showing a rim-enhanced mass with central cystic changes were retrospectively reviewed. All cases underwent dynamic contrast-enhanced MRI and 31 of them underwent diffusion-weighted imaging (DWI). Morphological features, dynamic parameters and apparent diffusion coefficient (ADC) values were comparatively analyzed using univariate analysis and binary logistic regression analysis.<h4>Results</h4>Breast cancer had a significantly thicker wall than the inflammatory breast diseases (P<0.001) while internal enhancing septa were more common in inflammatory breast diseases (P=0.003). On DWI, 86.7% of breast cancers demonstrate a peripheral hyperintensity whereas 93.8% of inflammatory breast diseases had a central hyperintensity (P<0.001). Compared to the inflammatory breast diseases, breast cancers had a lower ADC value for the wall (1.09 × 10(-3) mm(2)/s vs 1.42 × 10(-3) mm2/s, P<0.001) and a higher ADC value for the central part (1.94 × 10(-3) mm(2)/s vs 1.05 × 10(-3) mm(2)/s, P<0.001).<h4>Conclusions</h4>Both breast cancer and inflammatory breast diseases could present as a rim-enhanced mass with central cystic changes on MRI. Integrated analysis of the MR findings can allow for an accurate differential diagnosis. |
| format | Article |
| id | doaj-art-cbd4a0895c9c4880bef17dfde5f6f077 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-cbd4a0895c9c4880bef17dfde5f6f0772025-08-20T02:15:19ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0193e9035510.1371/journal.pone.0090355A rim-enhanced mass with central cystic changes on MR imaging: how to distinguish breast cancer from inflammatory breast diseases?Lijun WangDengbin WangXiaochun FeiMei RuanWeimin ChaiLin XuXiaoxiao Li<h4>Objective</h4>To evaluate the capacity of magnetic resonance imaging (MRI) to distinguish breast cancer from inflammatory breast diseases manifesting as a rim-enhanced mass with central cystic changes.<h4>Materials and methods</h4>Forty cases of breast cancer and 52 of inflammatory breast diseases showing a rim-enhanced mass with central cystic changes were retrospectively reviewed. All cases underwent dynamic contrast-enhanced MRI and 31 of them underwent diffusion-weighted imaging (DWI). Morphological features, dynamic parameters and apparent diffusion coefficient (ADC) values were comparatively analyzed using univariate analysis and binary logistic regression analysis.<h4>Results</h4>Breast cancer had a significantly thicker wall than the inflammatory breast diseases (P<0.001) while internal enhancing septa were more common in inflammatory breast diseases (P=0.003). On DWI, 86.7% of breast cancers demonstrate a peripheral hyperintensity whereas 93.8% of inflammatory breast diseases had a central hyperintensity (P<0.001). Compared to the inflammatory breast diseases, breast cancers had a lower ADC value for the wall (1.09 × 10(-3) mm(2)/s vs 1.42 × 10(-3) mm2/s, P<0.001) and a higher ADC value for the central part (1.94 × 10(-3) mm(2)/s vs 1.05 × 10(-3) mm(2)/s, P<0.001).<h4>Conclusions</h4>Both breast cancer and inflammatory breast diseases could present as a rim-enhanced mass with central cystic changes on MRI. Integrated analysis of the MR findings can allow for an accurate differential diagnosis.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090355&type=printable |
| spellingShingle | Lijun Wang Dengbin Wang Xiaochun Fei Mei Ruan Weimin Chai Lin Xu Xiaoxiao Li A rim-enhanced mass with central cystic changes on MR imaging: how to distinguish breast cancer from inflammatory breast diseases? PLoS ONE |
| title | A rim-enhanced mass with central cystic changes on MR imaging: how to distinguish breast cancer from inflammatory breast diseases? |
| title_full | A rim-enhanced mass with central cystic changes on MR imaging: how to distinguish breast cancer from inflammatory breast diseases? |
| title_fullStr | A rim-enhanced mass with central cystic changes on MR imaging: how to distinguish breast cancer from inflammatory breast diseases? |
| title_full_unstemmed | A rim-enhanced mass with central cystic changes on MR imaging: how to distinguish breast cancer from inflammatory breast diseases? |
| title_short | A rim-enhanced mass with central cystic changes on MR imaging: how to distinguish breast cancer from inflammatory breast diseases? |
| title_sort | rim enhanced mass with central cystic changes on mr imaging how to distinguish breast cancer from inflammatory breast diseases |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0090355&type=printable |
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