ACUTE DECOMPENSATION OF HYPERTENSIVE HEART DISEASE IN PATIENT WITH MALIGNANT URINARY BLADDER PARAGANGLIOMA: STAGES OF DIAGNOSTICS AND TREATMENT

Hypertensive heart disease with biventricular cardiac failure is not common in clinical practice. This diagnosis requires an extensive diagnostic search. We present the clinical case of the male patient of 38 aged. He was admitted to the clinic with heart failure 3-4 NYHA class. EchoCG revealed symm...

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Main Authors: O. V. Blagova, I. N. Alijeva, E. A. Bezrukov, L. I. Ippolitov, G. V. Polunin, E. A. Kogan, V. V. Sedov, E. A. Mershina, V. E. Sinitsyn, N. D. Sarkisova, A. V. Nedostup, V. V. Fomin
Format: Article
Language:English
Published: Столичная издательская компания 2018-07-01
Series:Рациональная фармакотерапия в кардиологии
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Online Access:https://www.rpcardio.online/jour/article/view/1692
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author O. V. Blagova
I. N. Alijeva
E. A. Bezrukov
L. I. Ippolitov
G. V. Polunin
E. A. Kogan
V. V. Sedov
E. A. Mershina
V. E. Sinitsyn
N. D. Sarkisova
A. V. Nedostup
V. V. Fomin
author_facet O. V. Blagova
I. N. Alijeva
E. A. Bezrukov
L. I. Ippolitov
G. V. Polunin
E. A. Kogan
V. V. Sedov
E. A. Mershina
V. E. Sinitsyn
N. D. Sarkisova
A. V. Nedostup
V. V. Fomin
author_sort O. V. Blagova
collection DOAJ
description Hypertensive heart disease with biventricular cardiac failure is not common in clinical practice. This diagnosis requires an extensive diagnostic search. We present the clinical case of the male patient of 38 aged. He was admitted to the clinic with heart failure 3-4 NYHA class. EchoCG revealed symmetric hypertrophy of the left ventricle up to 18 mm without its dilatation, a decrease in ejection fraction up to 42%, restrictive hemodynamics, overload of the right chambers, severe pulmonary hypertension (60 mm Hg). The clinical status included persistent arterial hypertension (180-220 and 120-150 mm Hg), effusion in both pleural cavities and pericardium, ascites, renal failure. During examination (multispiral computed tomography, magnetic resonance imaging, scintigraphy with 131I-MIBG), bladder paraganglioma was diagnosed (normatenafrin 1468 μg/day). The resection of the tumor was performed, according to immunohistochemical research – neuroendocrine carcinoma, G1. After 3 months a partial regression of hypertension and cardiac failure was observed with the preservation of a high level of creatinine. The criteria and differential diagnosis of the hypertensive heart disease and the syndrome of primary myocardial hypertrophy, diagnostics of the urinary bladder paraganglioma, complex mechanisms of myocardial damage within the pheochromocytoma and its prognosis are discussed.
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series Рациональная фармакотерапия в кардиологии
spelling doaj-art-cbcdec3eff1242168d1d746b3c4cbe742025-08-23T10:00:29ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532018-07-0114337037810.20996/1819-6446-2018-14-3-370-3781484ACUTE DECOMPENSATION OF HYPERTENSIVE HEART DISEASE IN PATIENT WITH MALIGNANT URINARY BLADDER PARAGANGLIOMA: STAGES OF DIAGNOSTICS AND TREATMENTO. V. Blagova0I. N. Alijeva1E. A. Bezrukov2L. I. Ippolitov3G. V. Polunin4E. A. Kogan5V. V. Sedov6E. A. Mershina7V. E. Sinitsyn8N. D. Sarkisova9A. V. Nedostup10V. V. Fomin11I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)Federal Center of Treatment and RehabilitationFederal Center of Treatment and RehabilitationI.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)I.M. Sechenov First Moscow State Medical University (Sechenov University)Hypertensive heart disease with biventricular cardiac failure is not common in clinical practice. This diagnosis requires an extensive diagnostic search. We present the clinical case of the male patient of 38 aged. He was admitted to the clinic with heart failure 3-4 NYHA class. EchoCG revealed symmetric hypertrophy of the left ventricle up to 18 mm without its dilatation, a decrease in ejection fraction up to 42%, restrictive hemodynamics, overload of the right chambers, severe pulmonary hypertension (60 mm Hg). The clinical status included persistent arterial hypertension (180-220 and 120-150 mm Hg), effusion in both pleural cavities and pericardium, ascites, renal failure. During examination (multispiral computed tomography, magnetic resonance imaging, scintigraphy with 131I-MIBG), bladder paraganglioma was diagnosed (normatenafrin 1468 μg/day). The resection of the tumor was performed, according to immunohistochemical research – neuroendocrine carcinoma, G1. After 3 months a partial regression of hypertension and cardiac failure was observed with the preservation of a high level of creatinine. The criteria and differential diagnosis of the hypertensive heart disease and the syndrome of primary myocardial hypertrophy, diagnostics of the urinary bladder paraganglioma, complex mechanisms of myocardial damage within the pheochromocytoma and its prognosis are discussed.https://www.rpcardio.online/jour/article/view/1692malignant hypertensionhypertonic heart diseaseacute cardiac failureprimary myocardial hypertrophy syndromemalignant paraganglioma of the urinary bladderneuroendocrine carcinomaimmunohistochemical study
spellingShingle O. V. Blagova
I. N. Alijeva
E. A. Bezrukov
L. I. Ippolitov
G. V. Polunin
E. A. Kogan
V. V. Sedov
E. A. Mershina
V. E. Sinitsyn
N. D. Sarkisova
A. V. Nedostup
V. V. Fomin
ACUTE DECOMPENSATION OF HYPERTENSIVE HEART DISEASE IN PATIENT WITH MALIGNANT URINARY BLADDER PARAGANGLIOMA: STAGES OF DIAGNOSTICS AND TREATMENT
Рациональная фармакотерапия в кардиологии
malignant hypertension
hypertonic heart disease
acute cardiac failure
primary myocardial hypertrophy syndrome
malignant paraganglioma of the urinary bladder
neuroendocrine carcinoma
immunohistochemical study
title ACUTE DECOMPENSATION OF HYPERTENSIVE HEART DISEASE IN PATIENT WITH MALIGNANT URINARY BLADDER PARAGANGLIOMA: STAGES OF DIAGNOSTICS AND TREATMENT
title_full ACUTE DECOMPENSATION OF HYPERTENSIVE HEART DISEASE IN PATIENT WITH MALIGNANT URINARY BLADDER PARAGANGLIOMA: STAGES OF DIAGNOSTICS AND TREATMENT
title_fullStr ACUTE DECOMPENSATION OF HYPERTENSIVE HEART DISEASE IN PATIENT WITH MALIGNANT URINARY BLADDER PARAGANGLIOMA: STAGES OF DIAGNOSTICS AND TREATMENT
title_full_unstemmed ACUTE DECOMPENSATION OF HYPERTENSIVE HEART DISEASE IN PATIENT WITH MALIGNANT URINARY BLADDER PARAGANGLIOMA: STAGES OF DIAGNOSTICS AND TREATMENT
title_short ACUTE DECOMPENSATION OF HYPERTENSIVE HEART DISEASE IN PATIENT WITH MALIGNANT URINARY BLADDER PARAGANGLIOMA: STAGES OF DIAGNOSTICS AND TREATMENT
title_sort acute decompensation of hypertensive heart disease in patient with malignant urinary bladder paraganglioma stages of diagnostics and treatment
topic malignant hypertension
hypertonic heart disease
acute cardiac failure
primary myocardial hypertrophy syndrome
malignant paraganglioma of the urinary bladder
neuroendocrine carcinoma
immunohistochemical study
url https://www.rpcardio.online/jour/article/view/1692
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