Vitamin D3 Suppresses Class II Invariant Chain Peptide Expression on Activated B-Lymphocytes: A Plausible Mechanism for Downregulation of Acute Inflammatory Conditions

Vitamin D3 Suppresses Class II Invariant Chain Peptide Expression on Activated B-Lymphocytes: A Plausible Mechanism for Downregulation of Acute Inflammatory Conditions

Class II invariant chain peptide (CLIP) expression has been demonstrated to play a pivotal role in the regulation of B cell function after nonspecific polyclonal expansion. Several studies have shown vitamin D3 helps regulate the immune response. We hypothesized that activated vitamin D3 suppresses...

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Bibliographic Details
Main Authors: Omar K. Danner, Leslie R. Matthews, Sharon Francis, Veena N. Rao, Cassie P. Harvey, Richard P. Tobin, Ken L. Wilson, Ernest Alema-Mensah, M. Karen Newell Rogers, Ed W. Childs
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Nutrition and Metabolism
Online Access:http://dx.doi.org/10.1155/2016/4280876
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