Sentinel node biopsy for skin melanoma
Background/Aim. Skin melanoma is one of the most malignant diseases with increasing incidence rate. Sentinel node biopsy (SNB) is very important for early detection of metastatic spread. The aim of the study was to analyze the first 40 patients with skin melanoma of 1 to 4 mm Breslow thickness when...
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| Format: | Article |
| Language: | English |
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Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade
2009-01-01
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| Series: | Vojnosanitetski Pregled |
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| Online Access: | http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500908657K.pdf |
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| _version_ | 1849684038620545024 |
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| author | Kovačević Predrag Višnjić Milan Vlajković Marina Kovačević Tatjana Višnjić Aleksandar |
| author_facet | Kovačević Predrag Višnjić Milan Vlajković Marina Kovačević Tatjana Višnjić Aleksandar |
| author_sort | Kovačević Predrag |
| collection | DOAJ |
| description | Background/Aim. Skin melanoma is one of the most malignant diseases with increasing incidence rate. Sentinel node biopsy (SNB) is very important for early detection of metastatic spread. The aim of the study was to analyze the first 40 patients with skin melanoma of 1 to 4 mm Breslow thickness when SNB was indicated. Methods. The patient characteristics, localization of the primary melanoma as well as histology grade were analyzed. SNB with intraoperative radiocolloid and methylene blue dye detection was performed. Results. Complication rate after SNB was analyzed and seroma was found in 5% of the patients. The therapeutic node dissection was performed in 10 patients with positive sentinel biopsy. The follow-up lasted two years. In five patients the false negative SNB was defined after the mean time of 11 months and the therapeutic dissection was performed. Conclusion. SNB in melanoma patients is a useful diagnostic procedure. It is advised for melanoma of 1 to 4 mm Breslow thickness. |
| format | Article |
| id | doaj-art-cbc374c864c34e2d9a4d1c2c7ff60c7c |
| institution | DOAJ |
| issn | 0042-8450 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade |
| record_format | Article |
| series | Vojnosanitetski Pregled |
| spelling | doaj-art-cbc374c864c34e2d9a4d1c2c7ff60c7c2025-08-20T03:23:35ZengMinistry of Defence of the Republic of Serbia, University of Defence, BelgradeVojnosanitetski Pregled0042-84502009-01-0166865766210.2298/VSP0908657KSentinel node biopsy for skin melanomaKovačević PredragVišnjić MilanVlajković MarinaKovačević TatjanaVišnjić AleksandarBackground/Aim. Skin melanoma is one of the most malignant diseases with increasing incidence rate. Sentinel node biopsy (SNB) is very important for early detection of metastatic spread. The aim of the study was to analyze the first 40 patients with skin melanoma of 1 to 4 mm Breslow thickness when SNB was indicated. Methods. The patient characteristics, localization of the primary melanoma as well as histology grade were analyzed. SNB with intraoperative radiocolloid and methylene blue dye detection was performed. Results. Complication rate after SNB was analyzed and seroma was found in 5% of the patients. The therapeutic node dissection was performed in 10 patients with positive sentinel biopsy. The follow-up lasted two years. In five patients the false negative SNB was defined after the mean time of 11 months and the therapeutic dissection was performed. Conclusion. SNB in melanoma patients is a useful diagnostic procedure. It is advised for melanoma of 1 to 4 mm Breslow thickness.http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500908657K.pdfmelanomaskin neoplasmssentinel lymph node biopsyorganotechnetium compoundsmethylene bluedissection |
| spellingShingle | Kovačević Predrag Višnjić Milan Vlajković Marina Kovačević Tatjana Višnjić Aleksandar Sentinel node biopsy for skin melanoma Vojnosanitetski Pregled melanoma skin neoplasms sentinel lymph node biopsy organotechnetium compounds methylene blue dissection |
| title | Sentinel node biopsy for skin melanoma |
| title_full | Sentinel node biopsy for skin melanoma |
| title_fullStr | Sentinel node biopsy for skin melanoma |
| title_full_unstemmed | Sentinel node biopsy for skin melanoma |
| title_short | Sentinel node biopsy for skin melanoma |
| title_sort | sentinel node biopsy for skin melanoma |
| topic | melanoma skin neoplasms sentinel lymph node biopsy organotechnetium compounds methylene blue dissection |
| url | http://www.doiserbia.nb.rs/img/doi/0042-8450/2009/0042-84500908657K.pdf |
| work_keys_str_mv | AT kovacevicpredrag sentinelnodebiopsyforskinmelanoma AT visnjicmilan sentinelnodebiopsyforskinmelanoma AT vlajkovicmarina sentinelnodebiopsyforskinmelanoma AT kovacevictatjana sentinelnodebiopsyforskinmelanoma AT visnjicaleksandar sentinelnodebiopsyforskinmelanoma |