Severe Hypercalcemia as Presentation of Atypical Cystic Parathyroid Adenoma: A Case Report
Because of their similarities with parathyroid carcinomas, atypical parathyroid adenomas constitute a challenge for pathologists. The diagnosis of this kind of parathyroid tumor also can be difficult for clinicians because of the low accuracy of imaging techniques such as scintigraphy with technetiu...
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| Format: | Article |
| Language: | English |
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American College of Physicians
2024-09-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2023.1333 |
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| author | Paola G. Donoso Naranjo Macarena Naranjo Arellano Esteban Castillo Sánchez-Heredero Isabel Martín Garrido |
| author_facet | Paola G. Donoso Naranjo Macarena Naranjo Arellano Esteban Castillo Sánchez-Heredero Isabel Martín Garrido |
| author_sort | Paola G. Donoso Naranjo |
| collection | DOAJ |
| description | Because of their similarities with parathyroid carcinomas, atypical parathyroid adenomas constitute a challenge for pathologists. The diagnosis of this kind of parathyroid tumor also can be difficult for clinicians because of the low accuracy of imaging techniques such as scintigraphy with technetium (Tc)-99m-sestamibi or ultrasonography of the neck, severe hypercalcemia, and high serum levels of intact parathyroid hormone. We present an unusual case of hyperparathyroidism caused by an atypical cystic parathyroid adenoma with hypercalcemia and negative scintigraphy that required dialysis and presented with several postoperative complications. The clinical presentation may have indicated a parathyroid carcinoma; however, a histopathologic diagnosis was key to the diagnosis. |
| format | Article |
| id | doaj-art-cbbf429094b143478560e119fc0a5ba0 |
| institution | DOAJ |
| issn | 2767-7664 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | American College of Physicians |
| record_format | Article |
| series | Annals of Internal Medicine: Clinical Cases |
| spelling | doaj-art-cbbf429094b143478560e119fc0a5ba02025-08-20T03:18:46ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-09-013910.7326/aimcc.2023.1333Severe Hypercalcemia as Presentation of Atypical Cystic Parathyroid Adenoma: A Case ReportPaola G. Donoso Naranjo0Macarena Naranjo Arellano1Esteban Castillo Sánchez-Heredero2Isabel Martín Garrido31Nephrology Department, Virgen del Rocío University Hospital, Seville, Spain1Nephrology Department, Virgen del Rocío University Hospital, Seville, Spain2Pathology Department, Virgen del Rocío University Hospital, Seville, Spain3Internal Medicine Department, Virgen del Rocío University Hospital, Seville, SpainBecause of their similarities with parathyroid carcinomas, atypical parathyroid adenomas constitute a challenge for pathologists. The diagnosis of this kind of parathyroid tumor also can be difficult for clinicians because of the low accuracy of imaging techniques such as scintigraphy with technetium (Tc)-99m-sestamibi or ultrasonography of the neck, severe hypercalcemia, and high serum levels of intact parathyroid hormone. We present an unusual case of hyperparathyroidism caused by an atypical cystic parathyroid adenoma with hypercalcemia and negative scintigraphy that required dialysis and presented with several postoperative complications. The clinical presentation may have indicated a parathyroid carcinoma; however, a histopathologic diagnosis was key to the diagnosis.https://www.acpjournals.org/doi/10.7326/aimcc.2023.1333 |
| spellingShingle | Paola G. Donoso Naranjo Macarena Naranjo Arellano Esteban Castillo Sánchez-Heredero Isabel Martín Garrido Severe Hypercalcemia as Presentation of Atypical Cystic Parathyroid Adenoma: A Case Report Annals of Internal Medicine: Clinical Cases |
| title | Severe Hypercalcemia as Presentation of Atypical Cystic Parathyroid Adenoma: A Case Report |
| title_full | Severe Hypercalcemia as Presentation of Atypical Cystic Parathyroid Adenoma: A Case Report |
| title_fullStr | Severe Hypercalcemia as Presentation of Atypical Cystic Parathyroid Adenoma: A Case Report |
| title_full_unstemmed | Severe Hypercalcemia as Presentation of Atypical Cystic Parathyroid Adenoma: A Case Report |
| title_short | Severe Hypercalcemia as Presentation of Atypical Cystic Parathyroid Adenoma: A Case Report |
| title_sort | severe hypercalcemia as presentation of atypical cystic parathyroid adenoma a case report |
| url | https://www.acpjournals.org/doi/10.7326/aimcc.2023.1333 |
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