Long QT Syndrome Course Associated with New Coronavirus Infection. Clinical Case

Background. Long QT syndrome is hereditary disease, cardiac canalopathy variant, characterized by syncope and high risk of sudden cardiac death due to occurrence of polymorphic ventricular tachycardia (VT), torsade de pointes, and ventricular fibrillation. Acute respiratory viral infection may aggra...

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Main Authors: Sabina Kh. Israfilova, Tatiana K. Kruchina, Marina V. Zhdanova, Lada О. Klimenko, Novik A. Gennadiy
Format: Article
Language:English
Published: "Paediatrician" Publishers LLC 2025-02-01
Series:Вопросы современной педиатрии
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Online Access:https://vsp.spr-journal.ru/jour/article/view/3682
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author Sabina Kh. Israfilova
Tatiana K. Kruchina
Marina V. Zhdanova
Lada О. Klimenko
Novik A. Gennadiy
author_facet Sabina Kh. Israfilova
Tatiana K. Kruchina
Marina V. Zhdanova
Lada О. Klimenko
Novik A. Gennadiy
author_sort Sabina Kh. Israfilova
collection DOAJ
description Background. Long QT syndrome is hereditary disease, cardiac canalopathy variant, characterized by syncope and high risk of sudden cardiac death due to occurrence of polymorphic ventricular tachycardia (VT), torsade de pointes, and ventricular fibrillation. Acute respiratory viral infection may aggravate clinical course of primary electrical heart diseases. Clinical case description. 14-year-old female patient was transferred to infectious diseases hospital from another hospital with positive PCR test on new coronavirus infection (COVID-19) after loss of consciousness in November 2021. Syncope was first noted at the age of 12, however then did not recur, and their examination and treatment were postponed due to the COVID-19 pandemic. Syncopal states continued during COVID-19. Cardiac examination was performed at infectious diseases hospital: recurrent VT, torsade de pointes, was diagnosed along with QT interval prolongation. The girl's condition has improved after the treatment and selection of antiarrhythmic therapy. 15 days later negative PCR test for SARS-CoV-2 was received, and the patient was transferred to specialized hospital, where the long QT syndrome was confirmed, and dual-chamber cardioverter defibrillator was installed. Conclusion. This clinical case demonstrates that ARVI can aggravate the course of existing primary arrhythmia and emphasizes the crucial role of timely diagnosis and integrated approach to the management of patients with genetically determined cardiac arrhythmias.
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spelling doaj-art-cbbbc7df4d6c4e258dd418c8615d71702025-08-20T03:59:54Zeng"Paediatrician" Publishers LLCВопросы современной педиатрии1682-55271682-55352025-02-0124110.15690/vsp.v24i1.28632221Long QT Syndrome Course Associated with New Coronavirus Infection. Clinical CaseSabina Kh. Israfilova0Tatiana K. Kruchina1Marina V. Zhdanova2Lada О. Klimenko3Novik A. Gennadiy4Children’s City Hospital №5 named after N.F. Filatov; Saint Petersburg State Pediatric Medical UniversitySaint Petersburg State Pediatric Medical UniversitySaint Petersburg State Pediatric Medical UniversitySaint Petersburg State Pediatric Medical UniversitySaint Petersburg State Pediatric Medical UniversityBackground. Long QT syndrome is hereditary disease, cardiac canalopathy variant, characterized by syncope and high risk of sudden cardiac death due to occurrence of polymorphic ventricular tachycardia (VT), torsade de pointes, and ventricular fibrillation. Acute respiratory viral infection may aggravate clinical course of primary electrical heart diseases. Clinical case description. 14-year-old female patient was transferred to infectious diseases hospital from another hospital with positive PCR test on new coronavirus infection (COVID-19) after loss of consciousness in November 2021. Syncope was first noted at the age of 12, however then did not recur, and their examination and treatment were postponed due to the COVID-19 pandemic. Syncopal states continued during COVID-19. Cardiac examination was performed at infectious diseases hospital: recurrent VT, torsade de pointes, was diagnosed along with QT interval prolongation. The girl's condition has improved after the treatment and selection of antiarrhythmic therapy. 15 days later negative PCR test for SARS-CoV-2 was received, and the patient was transferred to specialized hospital, where the long QT syndrome was confirmed, and dual-chamber cardioverter defibrillator was installed. Conclusion. This clinical case demonstrates that ARVI can aggravate the course of existing primary arrhythmia and emphasizes the crucial role of timely diagnosis and integrated approach to the management of patients with genetically determined cardiac arrhythmias.https://vsp.spr-journal.ru/jour/article/view/3682long qt syndromeventricular arrhythmiaacute respiratory viral infectioncovid-19children
spellingShingle Sabina Kh. Israfilova
Tatiana K. Kruchina
Marina V. Zhdanova
Lada О. Klimenko
Novik A. Gennadiy
Long QT Syndrome Course Associated with New Coronavirus Infection. Clinical Case
Вопросы современной педиатрии
long qt syndrome
ventricular arrhythmia
acute respiratory viral infection
covid-19
children
title Long QT Syndrome Course Associated with New Coronavirus Infection. Clinical Case
title_full Long QT Syndrome Course Associated with New Coronavirus Infection. Clinical Case
title_fullStr Long QT Syndrome Course Associated with New Coronavirus Infection. Clinical Case
title_full_unstemmed Long QT Syndrome Course Associated with New Coronavirus Infection. Clinical Case
title_short Long QT Syndrome Course Associated with New Coronavirus Infection. Clinical Case
title_sort long qt syndrome course associated with new coronavirus infection clinical case
topic long qt syndrome
ventricular arrhythmia
acute respiratory viral infection
covid-19
children
url https://vsp.spr-journal.ru/jour/article/view/3682
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AT tatianakkruchina longqtsyndromecourseassociatedwithnewcoronavirusinfectionclinicalcase
AT marinavzhdanova longqtsyndromecourseassociatedwithnewcoronavirusinfectionclinicalcase
AT ladaoklimenko longqtsyndromecourseassociatedwithnewcoronavirusinfectionclinicalcase
AT novikagennadiy longqtsyndromecourseassociatedwithnewcoronavirusinfectionclinicalcase