Effect of hydrogen sulfide on the contractile activity of smooth muscle cells from the rat aorta
In preparations of rat aorta, used as a model of muscular type arteries, the method mehanografii studied the effect of hydrogen sulfide on the reduction of isolated of vascular smooth muscle. Found that hydrogen sulfide in concentrations 1—50 mmol increases the mechanical stress of smooth muscle in...
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2010-12-01
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| Series: | Бюллетень сибирской медицины |
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| Online Access: | https://bulletin.ssmu.ru/jour/article/view/1693 |
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| author | M. B. Baskakov S. V. Gusakova A. S. Zheludeva L. V. Smagly I. V. Kovalyov T. A. Vtorushina D. S. Nosov K. V. Yeryomenko M. A. Medvedev S. N. Orlov |
| author_facet | M. B. Baskakov S. V. Gusakova A. S. Zheludeva L. V. Smagly I. V. Kovalyov T. A. Vtorushina D. S. Nosov K. V. Yeryomenko M. A. Medvedev S. N. Orlov |
| author_sort | M. B. Baskakov |
| collection | DOAJ |
| description | In preparations of rat aorta, used as a model of muscular type arteries, the method mehanografii studied the effect of hydrogen sulfide on the reduction of isolated of vascular smooth muscle. Found that hydrogen sulfide in concentrations 1—50 mmol increases the mechanical stress of smooth muscle in high-K + medium. At higher concentrations (300—1 000 mmol) H2S leads to lower amplitude giperkalievoy contraction in high-K + medium. Reduction of smooth muscle cells caused by phenylephrine inhibited the action of hydrogen sulfide in the whole range of concentrations. The causes of differences in data obtained with the results of studies in other laboratories, and possible mechanisms of action of hydrogen sulfide on the contractile activity of vascular smooth muscle. |
| format | Article |
| id | doaj-art-cbbafb2195f5464fa043b7b9332944ed |
| institution | DOAJ |
| issn | 1682-0363 1819-3684 |
| language | English |
| publishDate | 2010-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj-art-cbbafb2195f5464fa043b7b9332944ed2025-08-20T03:02:22ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842010-12-0196121710.20538/1682-0363-2010-6-12-171192Effect of hydrogen sulfide on the contractile activity of smooth muscle cells from the rat aortaM. B. Baskakov0S. V. Gusakova1A. S. Zheludeva2L. V. Smagly3I. V. Kovalyov4T. A. Vtorushina5D. S. Nosov6K. V. Yeryomenko7M. A. Medvedev8S. N. Orlov9Сибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетСибирский государственный медицинский университетУниверситет г. МонреаляIn preparations of rat aorta, used as a model of muscular type arteries, the method mehanografii studied the effect of hydrogen sulfide on the reduction of isolated of vascular smooth muscle. Found that hydrogen sulfide in concentrations 1—50 mmol increases the mechanical stress of smooth muscle in high-K + medium. At higher concentrations (300—1 000 mmol) H2S leads to lower amplitude giperkalievoy contraction in high-K + medium. Reduction of smooth muscle cells caused by phenylephrine inhibited the action of hydrogen sulfide in the whole range of concentrations. The causes of differences in data obtained with the results of studies in other laboratories, and possible mechanisms of action of hydrogen sulfide on the contractile activity of vascular smooth muscle.https://bulletin.ssmu.ru/jour/article/view/1693smooth muscle cellsgasotransmitterhydrogen sulfide |
| spellingShingle | M. B. Baskakov S. V. Gusakova A. S. Zheludeva L. V. Smagly I. V. Kovalyov T. A. Vtorushina D. S. Nosov K. V. Yeryomenko M. A. Medvedev S. N. Orlov Effect of hydrogen sulfide on the contractile activity of smooth muscle cells from the rat aorta Бюллетень сибирской медицины smooth muscle cells gasotransmitter hydrogen sulfide |
| title | Effect of hydrogen sulfide on the contractile activity of smooth muscle cells from the rat aorta |
| title_full | Effect of hydrogen sulfide on the contractile activity of smooth muscle cells from the rat aorta |
| title_fullStr | Effect of hydrogen sulfide on the contractile activity of smooth muscle cells from the rat aorta |
| title_full_unstemmed | Effect of hydrogen sulfide on the contractile activity of smooth muscle cells from the rat aorta |
| title_short | Effect of hydrogen sulfide on the contractile activity of smooth muscle cells from the rat aorta |
| title_sort | effect of hydrogen sulfide on the contractile activity of smooth muscle cells from the rat aorta |
| topic | smooth muscle cells gasotransmitter hydrogen sulfide |
| url | https://bulletin.ssmu.ru/jour/article/view/1693 |
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