Enhancing nucleic acid delivery by the integration of artificial intelligence into lipid nanoparticle formulation

Enhancing nucleic acid delivery by the integration of artificial intelligence into lipid nanoparticle formulation

The advent of messenger RNA (mRNA) therapeutics has revolutionized medicine, with its potential underscored by rapid advancements during the COVID-19 pandemic. Despite its promise, nucleic acid delivery remains a formidable challenge due to enzymatic degradation, cellular uptake barriers, and endoso...

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Bibliographic Details
Main Authors: Kagya Amoako, Amir Mokhammad, Afrida Malik, Sumith Yesudasan, Anas Wheba, Oluwanifemi Olagunju, Sean X. Gu, Timur Yarovinsky, Edward Vincent S. Faustino, Juliane Nguyen, John Hwa
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Medical Technology
Subjects:
nucleic acid delivery
liposome nanoparticles
artificial intelligence
platelets
transfection
Online Access:https://www.frontiersin.org/articles/10.3389/fmedt.2025.1591119/full
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