Long lasting effects of perinatal exposure to the Chlorpyrifos pesticide on sleep, breathing, and neuroinflammation in adult mice.

Long lasting effects of perinatal exposure to the Chlorpyrifos pesticide on sleep, breathing, and neuroinflammation in adult mice.

Early-life exposure to environmental stressors may increase the risk of disease later in life. Chlorpyrifos (CPF), a widely used pesticide and acetylcholinesterase inhibitor, can cross the placental barrier and can be found in breast milk, leading to excessive cholinergic stimulation. Acetylcholine...

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Main Authors: Elena Miglioranza, Laura Rullo, Sara Alvente, Stefano Bastianini, Dario Coraci, Viviana Lo Martire, Loredana Maria Losapio, Gabriele Matteoli, Camilla Morosini, Emilia Volino, Alessandro Silvani, Roberto Rimondini, Sanzio Candeletti, Patrizia Romualdi, Giovanna Zoccoli, Chiara Berteotti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0328581
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