Estimation of cellular immune response by evaluation of some cytokines in immunopathogenesis of chronic hepatitis B and C pre- and post- treated Iraqi patients (in vivo and in vitro)
Two groups of chronic hepatitis B and C virus patients were divided into Pre-treated patients (25 CHB patients with positive HBs Ag for more than 6 months and 40 CHC patients), and post-treated patients [12 CHB patients (4, 6, and 2 were treated with lamivudine, IFN-? and combination of LMV + IFN-?...
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University of Baghdad, College of Science for Women
2009-09-01
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| Series: | مجلة بغداد للعلوم |
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| Online Access: | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1013 |
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| description | Two groups of chronic hepatitis B and C virus patients were divided into Pre-treated patients (25 CHB patients with positive HBs Ag for more than 6 months and 40 CHC patients), and post-treated patients [12 CHB patients (4, 6, and 2 were treated with lamivudine, IFN-? and combination of LMV + IFN-? respectively), and 27 patients for CHC (3, 13 and 11 patients were treated with Ribavirin, IFN-? and combination therapy (RBV+ IFN-?) respectively].These patients were followed up for 6 months.
By using ELISA technique, levels of IL-6, IL-10, IFN-? and TNF-? were measured in vivo and in vitro (supernatant of PBMCs stimulated with PHA) and compared with healthy control. The mean level of IL-6, IL-10 and TNF-? in CHB patients showed significant differences (P |
| format | Article |
| id | doaj-art-cbb26bd893d54af3af46a8a6a6373b54 |
| institution | Kabale University |
| issn | 2078-8665 2411-7986 |
| language | English |
| publishDate | 2009-09-01 |
| publisher | University of Baghdad, College of Science for Women |
| record_format | Article |
| series | مجلة بغداد للعلوم |
| spelling | doaj-art-cbb26bd893d54af3af46a8a6a6373b542025-08-20T03:38:50ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862009-09-016310.21123/bsj.6.3.533-541Estimation of cellular immune response by evaluation of some cytokines in immunopathogenesis of chronic hepatitis B and C pre- and post- treated Iraqi patients (in vivo and in vitro)Baghdad Science JournalTwo groups of chronic hepatitis B and C virus patients were divided into Pre-treated patients (25 CHB patients with positive HBs Ag for more than 6 months and 40 CHC patients), and post-treated patients [12 CHB patients (4, 6, and 2 were treated with lamivudine, IFN-? and combination of LMV + IFN-? respectively), and 27 patients for CHC (3, 13 and 11 patients were treated with Ribavirin, IFN-? and combination therapy (RBV+ IFN-?) respectively].These patients were followed up for 6 months. By using ELISA technique, levels of IL-6, IL-10, IFN-? and TNF-? were measured in vivo and in vitro (supernatant of PBMCs stimulated with PHA) and compared with healthy control. The mean level of IL-6, IL-10 and TNF-? in CHB patients showed significant differences (Phttp://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1013" Brucella melitensis, Streptococcus salivarius subsp. thermophilus , Lactobacillus delb" |
| spellingShingle | Baghdad Science Journal Estimation of cellular immune response by evaluation of some cytokines in immunopathogenesis of chronic hepatitis B and C pre- and post- treated Iraqi patients (in vivo and in vitro) مجلة بغداد للعلوم " Brucella melitensis, Streptococcus salivarius subsp. thermophilus , Lactobacillus delb" |
| title | Estimation of cellular immune response by evaluation of some cytokines in immunopathogenesis of chronic hepatitis B and C pre- and post- treated Iraqi patients (in vivo and in vitro) |
| title_full | Estimation of cellular immune response by evaluation of some cytokines in immunopathogenesis of chronic hepatitis B and C pre- and post- treated Iraqi patients (in vivo and in vitro) |
| title_fullStr | Estimation of cellular immune response by evaluation of some cytokines in immunopathogenesis of chronic hepatitis B and C pre- and post- treated Iraqi patients (in vivo and in vitro) |
| title_full_unstemmed | Estimation of cellular immune response by evaluation of some cytokines in immunopathogenesis of chronic hepatitis B and C pre- and post- treated Iraqi patients (in vivo and in vitro) |
| title_short | Estimation of cellular immune response by evaluation of some cytokines in immunopathogenesis of chronic hepatitis B and C pre- and post- treated Iraqi patients (in vivo and in vitro) |
| title_sort | estimation of cellular immune response by evaluation of some cytokines in immunopathogenesis of chronic hepatitis b and c pre and post treated iraqi patients in vivo and in vitro |
| topic | " Brucella melitensis, Streptococcus salivarius subsp. thermophilus , Lactobacillus delb" |
| url | http://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/1013 |
| work_keys_str_mv | AT baghdadsciencejournal estimationofcellularimmuneresponsebyevaluationofsomecytokinesinimmunopathogenesisofchronichepatitisbandcpreandposttreatediraqipatientsinvivoandinvitro |