Tea and coffee consumption and the 15-Year risk of cardiovascular events: the Isfahan cohort study (ICS)

Abstract Background This study aimed to investigate the association between tea and coffee consumption and the 15-year incidence of cardiovascular events and mortality among the Iranian population. Methods The present study Data were obtained from the Isfahan Cohort Study (ICS), a prospective cohort...

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Main Authors: Raza Amani-Beni, Masoumeh Sadeghi, Fatemeh Nouri, Bahar Darouei, Noushin Mohammadifard, Maryam Boshtam, Ramesh Hosseinkhani, Nizal Sarrafzadegan
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Nutrition Journal
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Online Access:https://doi.org/10.1186/s12937-025-01093-w
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author Raza Amani-Beni
Masoumeh Sadeghi
Fatemeh Nouri
Bahar Darouei
Noushin Mohammadifard
Maryam Boshtam
Ramesh Hosseinkhani
Nizal Sarrafzadegan
author_facet Raza Amani-Beni
Masoumeh Sadeghi
Fatemeh Nouri
Bahar Darouei
Noushin Mohammadifard
Maryam Boshtam
Ramesh Hosseinkhani
Nizal Sarrafzadegan
author_sort Raza Amani-Beni
collection DOAJ
description Abstract Background This study aimed to investigate the association between tea and coffee consumption and the 15-year incidence of cardiovascular events and mortality among the Iranian population. Methods The present study Data were obtained from the Isfahan Cohort Study (ICS), a prospective cohort study of ≥ 35-year-old healthy adults in central Iran from 2001 to 2017. This study was conducted using baseline data on tea and/or coffee consumption per day/week from ICS to identify the occurrence of any new cardiovascular events, including acute myocardial infarction (AMI), unstable angina (UA), stroke, cardiovascular disease (CVD), sudden cardiac death (SCD), cardiovascular mortality, and all-cause mortality. Results 5248 participants with complete data were included in the study. After full adjustments, compared to participants with the lowest tea intake, the risk of AMI was significantly higher for participants with the highest tea intake (hazard ratio (HR) = 1.83; 95% confidence interval (CI): 1.10, 3.07; p for trend = 0.060). Also, moderate-tea drinking was associated with a 66% increased risk of AMI compared to the lowest-tea drinking (HR = 1.66; 95%CI: 1.03, 2.70). No significant association was observed between tea consumption and other CVD events or all-cause mortality. Moreover, after full adjustment, no significant association was observed between tea intake above the median and cardiovascular events or all-cause mortality or between coffee consumption and study outcomes. Conclusions High tea consumption significantly increases the risk of AMI; however, high tea and coffee consumption had no significant association with other cardiovascular events. Future research is needed, especially in Iran and the Middle East, to clarify and evaluate more factors related to the complex nature of tea and coffee consumption and cardiovascular events.
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spelling doaj-art-cbb1fcd796d343839f71d25a0baf613c2025-08-20T02:16:40ZengBMCNutrition Journal1475-28912025-02-0124111010.1186/s12937-025-01093-wTea and coffee consumption and the 15-Year risk of cardiovascular events: the Isfahan cohort study (ICS)Raza Amani-Beni0Masoumeh Sadeghi1Fatemeh Nouri2Bahar Darouei3Noushin Mohammadifard4Maryam Boshtam5Ramesh Hosseinkhani6Nizal Sarrafzadegan7Interventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesCardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesIsfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesInterventional Cardiology Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesIsfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesIsfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesNoncommunicable Control Department, Vice Chancellery of Health, Isfahan University of Medical SciencesIsfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical SciencesAbstract Background This study aimed to investigate the association between tea and coffee consumption and the 15-year incidence of cardiovascular events and mortality among the Iranian population. Methods The present study Data were obtained from the Isfahan Cohort Study (ICS), a prospective cohort study of ≥ 35-year-old healthy adults in central Iran from 2001 to 2017. This study was conducted using baseline data on tea and/or coffee consumption per day/week from ICS to identify the occurrence of any new cardiovascular events, including acute myocardial infarction (AMI), unstable angina (UA), stroke, cardiovascular disease (CVD), sudden cardiac death (SCD), cardiovascular mortality, and all-cause mortality. Results 5248 participants with complete data were included in the study. After full adjustments, compared to participants with the lowest tea intake, the risk of AMI was significantly higher for participants with the highest tea intake (hazard ratio (HR) = 1.83; 95% confidence interval (CI): 1.10, 3.07; p for trend = 0.060). Also, moderate-tea drinking was associated with a 66% increased risk of AMI compared to the lowest-tea drinking (HR = 1.66; 95%CI: 1.03, 2.70). No significant association was observed between tea consumption and other CVD events or all-cause mortality. Moreover, after full adjustment, no significant association was observed between tea intake above the median and cardiovascular events or all-cause mortality or between coffee consumption and study outcomes. Conclusions High tea consumption significantly increases the risk of AMI; however, high tea and coffee consumption had no significant association with other cardiovascular events. Future research is needed, especially in Iran and the Middle East, to clarify and evaluate more factors related to the complex nature of tea and coffee consumption and cardiovascular events.https://doi.org/10.1186/s12937-025-01093-wTeaCoffeeCardiovascular diseasesMyocardial infarctionMortalityIran
spellingShingle Raza Amani-Beni
Masoumeh Sadeghi
Fatemeh Nouri
Bahar Darouei
Noushin Mohammadifard
Maryam Boshtam
Ramesh Hosseinkhani
Nizal Sarrafzadegan
Tea and coffee consumption and the 15-Year risk of cardiovascular events: the Isfahan cohort study (ICS)
Nutrition Journal
Tea
Coffee
Cardiovascular diseases
Myocardial infarction
Mortality
Iran
title Tea and coffee consumption and the 15-Year risk of cardiovascular events: the Isfahan cohort study (ICS)
title_full Tea and coffee consumption and the 15-Year risk of cardiovascular events: the Isfahan cohort study (ICS)
title_fullStr Tea and coffee consumption and the 15-Year risk of cardiovascular events: the Isfahan cohort study (ICS)
title_full_unstemmed Tea and coffee consumption and the 15-Year risk of cardiovascular events: the Isfahan cohort study (ICS)
title_short Tea and coffee consumption and the 15-Year risk of cardiovascular events: the Isfahan cohort study (ICS)
title_sort tea and coffee consumption and the 15 year risk of cardiovascular events the isfahan cohort study ics
topic Tea
Coffee
Cardiovascular diseases
Myocardial infarction
Mortality
Iran
url https://doi.org/10.1186/s12937-025-01093-w
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