Neuroendocrine Tumour in a 37-Year-Old Female: A Diagnostic Challenge
Pancreatic Neuroendocrine Tumours (PNETs) are a rare group of neoplasms arising from hormone-producing cells in the pancreas. Unlike the more common pancreatic adenocarcinomas, PNETs often grow more slowly and may produce hormones, leading to distinct clinical symptoms. We present a rare and diagnos...
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JCDR Research and Publications Private Limited
2025-08-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/article_fulltext.asp?issn=0973-709x&year=2025&month=August&volume=19&issue=8&page=PD11-PD14&id=21361 |
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| author | Manoj Dongare Parin Nilesh Patel Dakshyani Satish Nirhale Kishore Jeughle Siddharth Veerla |
| author_facet | Manoj Dongare Parin Nilesh Patel Dakshyani Satish Nirhale Kishore Jeughle Siddharth Veerla |
| author_sort | Manoj Dongare |
| collection | DOAJ |
| description | Pancreatic Neuroendocrine Tumours (PNETs) are a rare group of neoplasms arising from hormone-producing cells in the pancreas. Unlike the more common pancreatic adenocarcinomas, PNETs often grow more slowly and may produce hormones, leading to distinct clinical symptoms. We present a rare and diagnostically challenging case of a PNET in a 37-year-old female who presented with a three-month history of epigastric pain. Initial imaging studies revealed a mass in the liver, mimicking Hepatocellular Carcinoma (HCC), while subsequent investigations, including Positron Emission Tomography-Computed Tomography (PET-CT) and ultrasound-guided Fine-Needle Aspiration Cytology (FNAC), suggested a PNET. A Whipple procedure was performed, and histopathological examination confirmed the diagnosis. This case highlights the importance of a multidisciplinary approach in managing rare and challenging malignancies, emphasising the need for clinical vigilance, advanced imaging, and histopathological evaluation to confirm the diagnosis. The successful management of this case underscores the critical role of timely surgical intervention and personalised treatment strategies in achieving favourable outcomes. |
| format | Article |
| id | doaj-art-cbab29dd1dc14f46ade84fa67f7e7d9f |
| institution | Kabale University |
| issn | 2249-782X 0973-709X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj-art-cbab29dd1dc14f46ade84fa67f7e7d9f2025-08-20T04:00:32ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2025-08-01198PD11PD1410.7860/JCDR/2025/79747.21361Neuroendocrine Tumour in a 37-Year-Old Female: A Diagnostic ChallengeManoj Dongare0Parin Nilesh Patel1Dakshyani Satish Nirhale2Kishore Jeughle3Siddharth Veerla4Senior Consultant, General Surgery, Dr. D. Y. Patil Medical College and Hospital, Pune, Maharashtra, India.Junior Resident, General Surgery, Dr. D. Y. Patil Medical College and Hospital, Pune, Maharashtra, India.Professor and Head, General Surgery, Dr. D. Y. Patil Medical College and Hospital, Pune, Maharashtra, India.Associate Professor, General Surgery, Dr. D. Y. Patil Medical College and Hospital, Pune, Maharashtra, India.Junior Resident, General Surgery, Dr. D. Y. Patil Medical College and Hospital, Pune, Maharashtra, India.Pancreatic Neuroendocrine Tumours (PNETs) are a rare group of neoplasms arising from hormone-producing cells in the pancreas. Unlike the more common pancreatic adenocarcinomas, PNETs often grow more slowly and may produce hormones, leading to distinct clinical symptoms. We present a rare and diagnostically challenging case of a PNET in a 37-year-old female who presented with a three-month history of epigastric pain. Initial imaging studies revealed a mass in the liver, mimicking Hepatocellular Carcinoma (HCC), while subsequent investigations, including Positron Emission Tomography-Computed Tomography (PET-CT) and ultrasound-guided Fine-Needle Aspiration Cytology (FNAC), suggested a PNET. A Whipple procedure was performed, and histopathological examination confirmed the diagnosis. This case highlights the importance of a multidisciplinary approach in managing rare and challenging malignancies, emphasising the need for clinical vigilance, advanced imaging, and histopathological evaluation to confirm the diagnosis. The successful management of this case underscores the critical role of timely surgical intervention and personalised treatment strategies in achieving favourable outcomes.https://jcdr.net/article_fulltext.asp?issn=0973-709x&year=2025&month=August&volume=19&issue=8&page=PD11-PD14&id=21361case reportmalignancypancreatic masssurgical managementwhipple procedure |
| spellingShingle | Manoj Dongare Parin Nilesh Patel Dakshyani Satish Nirhale Kishore Jeughle Siddharth Veerla Neuroendocrine Tumour in a 37-Year-Old Female: A Diagnostic Challenge Journal of Clinical and Diagnostic Research case report malignancy pancreatic mass surgical management whipple procedure |
| title | Neuroendocrine Tumour in a 37-Year-Old Female: A Diagnostic Challenge |
| title_full | Neuroendocrine Tumour in a 37-Year-Old Female: A Diagnostic Challenge |
| title_fullStr | Neuroendocrine Tumour in a 37-Year-Old Female: A Diagnostic Challenge |
| title_full_unstemmed | Neuroendocrine Tumour in a 37-Year-Old Female: A Diagnostic Challenge |
| title_short | Neuroendocrine Tumour in a 37-Year-Old Female: A Diagnostic Challenge |
| title_sort | neuroendocrine tumour in a 37 year old female a diagnostic challenge |
| topic | case report malignancy pancreatic mass surgical management whipple procedure |
| url | https://jcdr.net/article_fulltext.asp?issn=0973-709x&year=2025&month=August&volume=19&issue=8&page=PD11-PD14&id=21361 |
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