A Rare Case of Small Bowel Ulceration Induced by COVID-19
Xizhuang Gao,1,* Lihao Shi,2,* Dehuai Jing,1 Cuimei Ma,1 Quanyi Wang,3 Jiehuan Wang,4 Fengqin Zhu,1 Mengmeng Zhao,1 Yun Chen,1 Guangxi Zhou1 1Department of Gastroenterology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272000,...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Dove Medical Press
2025-05-01
|
| Series: | Journal of Inflammation Research |
| Subjects: | |
| Online Access: | https://www.dovepress.com/a-rare-case-of-small-bowel-ulceration-induced-by-covid-19-peer-reviewed-fulltext-article-JIR |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849728508141502464 |
|---|---|
| author | Gao X Shi L Jing D Ma C Wang Q Wang J Zhu F Zhao M Chen Y Zhou G |
| author_facet | Gao X Shi L Jing D Ma C Wang Q Wang J Zhu F Zhao M Chen Y Zhou G |
| author_sort | Gao X |
| collection | DOAJ |
| description | Xizhuang Gao,1,* Lihao Shi,2,* Dehuai Jing,1 Cuimei Ma,1 Quanyi Wang,3 Jiehuan Wang,4 Fengqin Zhu,1 Mengmeng Zhao,1 Yun Chen,1 Guangxi Zhou1 1Department of Gastroenterology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272000, People’s Republic of China; 2Cheeloo College of Medicine, Shandong University, Jinan, 250012, People’s Republic of China; 3Department of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272000, People’s Republic of China; 4Department of Imaging, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guangxi Zhou, Department of Gastroenterology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272000, People’s Republic of China, Email zgx_viola@126.comBackground: COVID-19 can affect multiple organ systems beyond the respiratory tract, including the gastrointestinal tract, where gastrointestinal symptoms include nausea, vomiting, diarrhea, abdominal pain, and even serious manifestations such as ulcers, perforation, or gastrointestinal bleeding.Case Presentation: We report a case of a 45-year-old male patient with small bowel ulcers caused by chronic COVID-19 infection. Initially presenting with fever and transient unconsciousness, he developed ischemic necrosis and required a mid-thigh amputation. Despite treatment with anti-infection therapy, extracorporeal membrane oxygenation, and continuous renal replacement therapy, he experienced persistent abdominal pain and gastrointestinal bleeding. Imaging and colonoscopy confirmed partial small bowel obstruction and inflammation. After treatment with methylprednisolone and enteral nutrition, his symptoms improved. However, he suffered a gastrointestinal perforation requiring emergency surgery and later underwent a successful stoma reversal. The patient was subsequently discharged with improvement and was discharged with a primary diagnosis of “enterostomal status, perforation of small intestinal ulcer, viral myocarditis, COVID-19 infection, and post right lower extremity amputation”. During the past year of follow-up, the patient has not experienced any recurrence of abdominal pain or rectal bleeding.Conclusion: Although coronavirus pneumonia combined with small bowel ulcers is rare, it requires emergency treatment and has a high mortality rate. This case highlighted the severe gastrointestinal complications induced by COVID-19 infection and the effectiveness of comprehensive management strategies.Keywords: novel coronavirus, extrapulmonary manifestations, small bowel ulcers |
| format | Article |
| id | doaj-art-cb9fd6c7dfb54956aa8e2cde438bbced |
| institution | DOAJ |
| issn | 1178-7031 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Journal of Inflammation Research |
| spelling | doaj-art-cb9fd6c7dfb54956aa8e2cde438bbced2025-08-20T03:09:32ZengDove Medical PressJournal of Inflammation Research1178-70312025-05-01Volume 18Issue 161236131102847A Rare Case of Small Bowel Ulceration Induced by COVID-19Gao X0Shi L1Jing D2Ma C3Wang Q4Wang J5Zhu F6Zhao M7Chen Y8Zhou G9Department of GastroenterologyCheeloo College of MedicineDepartment of GastroenterologyDepartment of GastroenterologyDepartment of PathologyDepartment of RadiologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyDepartment of GastroenterologyXizhuang Gao,1,* Lihao Shi,2,* Dehuai Jing,1 Cuimei Ma,1 Quanyi Wang,3 Jiehuan Wang,4 Fengqin Zhu,1 Mengmeng Zhao,1 Yun Chen,1 Guangxi Zhou1 1Department of Gastroenterology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272000, People’s Republic of China; 2Cheeloo College of Medicine, Shandong University, Jinan, 250012, People’s Republic of China; 3Department of Pathology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272000, People’s Republic of China; 4Department of Imaging, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272000, People’s Republic of China*These authors contributed equally to this workCorrespondence: Guangxi Zhou, Department of Gastroenterology, Affiliated Hospital of Jining Medical University, Jining Medical University, Jining, Shandong, 272000, People’s Republic of China, Email zgx_viola@126.comBackground: COVID-19 can affect multiple organ systems beyond the respiratory tract, including the gastrointestinal tract, where gastrointestinal symptoms include nausea, vomiting, diarrhea, abdominal pain, and even serious manifestations such as ulcers, perforation, or gastrointestinal bleeding.Case Presentation: We report a case of a 45-year-old male patient with small bowel ulcers caused by chronic COVID-19 infection. Initially presenting with fever and transient unconsciousness, he developed ischemic necrosis and required a mid-thigh amputation. Despite treatment with anti-infection therapy, extracorporeal membrane oxygenation, and continuous renal replacement therapy, he experienced persistent abdominal pain and gastrointestinal bleeding. Imaging and colonoscopy confirmed partial small bowel obstruction and inflammation. After treatment with methylprednisolone and enteral nutrition, his symptoms improved. However, he suffered a gastrointestinal perforation requiring emergency surgery and later underwent a successful stoma reversal. The patient was subsequently discharged with improvement and was discharged with a primary diagnosis of “enterostomal status, perforation of small intestinal ulcer, viral myocarditis, COVID-19 infection, and post right lower extremity amputation”. During the past year of follow-up, the patient has not experienced any recurrence of abdominal pain or rectal bleeding.Conclusion: Although coronavirus pneumonia combined with small bowel ulcers is rare, it requires emergency treatment and has a high mortality rate. This case highlighted the severe gastrointestinal complications induced by COVID-19 infection and the effectiveness of comprehensive management strategies.Keywords: novel coronavirus, extrapulmonary manifestations, small bowel ulcershttps://www.dovepress.com/a-rare-case-of-small-bowel-ulceration-induced-by-covid-19-peer-reviewed-fulltext-article-JIRnovel coronavirusextrapulmonary manifestationssmall bowel ulcers |
| spellingShingle | Gao X Shi L Jing D Ma C Wang Q Wang J Zhu F Zhao M Chen Y Zhou G A Rare Case of Small Bowel Ulceration Induced by COVID-19 Journal of Inflammation Research novel coronavirus extrapulmonary manifestations small bowel ulcers |
| title | A Rare Case of Small Bowel Ulceration Induced by COVID-19 |
| title_full | A Rare Case of Small Bowel Ulceration Induced by COVID-19 |
| title_fullStr | A Rare Case of Small Bowel Ulceration Induced by COVID-19 |
| title_full_unstemmed | A Rare Case of Small Bowel Ulceration Induced by COVID-19 |
| title_short | A Rare Case of Small Bowel Ulceration Induced by COVID-19 |
| title_sort | rare case of small bowel ulceration induced by covid 19 |
| topic | novel coronavirus extrapulmonary manifestations small bowel ulcers |
| url | https://www.dovepress.com/a-rare-case-of-small-bowel-ulceration-induced-by-covid-19-peer-reviewed-fulltext-article-JIR |
| work_keys_str_mv | AT gaox ararecaseofsmallbowelulcerationinducedbycovid19 AT shil ararecaseofsmallbowelulcerationinducedbycovid19 AT jingd ararecaseofsmallbowelulcerationinducedbycovid19 AT mac ararecaseofsmallbowelulcerationinducedbycovid19 AT wangq ararecaseofsmallbowelulcerationinducedbycovid19 AT wangj ararecaseofsmallbowelulcerationinducedbycovid19 AT zhuf ararecaseofsmallbowelulcerationinducedbycovid19 AT zhaom ararecaseofsmallbowelulcerationinducedbycovid19 AT cheny ararecaseofsmallbowelulcerationinducedbycovid19 AT zhoug ararecaseofsmallbowelulcerationinducedbycovid19 AT gaox rarecaseofsmallbowelulcerationinducedbycovid19 AT shil rarecaseofsmallbowelulcerationinducedbycovid19 AT jingd rarecaseofsmallbowelulcerationinducedbycovid19 AT mac rarecaseofsmallbowelulcerationinducedbycovid19 AT wangq rarecaseofsmallbowelulcerationinducedbycovid19 AT wangj rarecaseofsmallbowelulcerationinducedbycovid19 AT zhuf rarecaseofsmallbowelulcerationinducedbycovid19 AT zhaom rarecaseofsmallbowelulcerationinducedbycovid19 AT cheny rarecaseofsmallbowelulcerationinducedbycovid19 AT zhoug rarecaseofsmallbowelulcerationinducedbycovid19 |