Options for Regenerative Treatment with Bone Grafts in Children with Anterior Lip/Palate Cleft—A Review
Anterior lip/palate cleft is a congenital deformity affecting the upper lip and palate, posing significant challenges in both aesthetic and functional aspects for children. Effective management of this condition is crucial for improving quality of life and ensuring normal development. This review ai...
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| Format: | Article |
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MDPI AG
2025-04-01
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| Series: | Children |
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| Online Access: | https://www.mdpi.com/2227-9067/12/5/559 |
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| author | Anna Miguel-Escribano Cosimo Galletti Juan de Quixano-Bardaji Francisco Real-Voltas Luca Fiorillo Maria Cuevas-Nunez Fulvia Galletti Javier Flores-Fraile |
| author_facet | Anna Miguel-Escribano Cosimo Galletti Juan de Quixano-Bardaji Francisco Real-Voltas Luca Fiorillo Maria Cuevas-Nunez Fulvia Galletti Javier Flores-Fraile |
| author_sort | Anna Miguel-Escribano |
| collection | DOAJ |
| description | Anterior lip/palate cleft is a congenital deformity affecting the upper lip and palate, posing significant challenges in both aesthetic and functional aspects for children. Effective management of this condition is crucial for improving quality of life and ensuring normal development. This review aims to highlight the regenerative treatment options available for children with anterior lip/palate cleft, focusing on the use of bone grafts and other advanced dental procedures. A review of the current literature and clinical practices was conducted to identify and evaluate the most effective treatment options. Emphasis was placed on regenerative techniques, particularly the use of bone grafts. Advancements in regenerative dentistry offer promising outcomes for children with anterior lip/palate cleft. Bone grafts, combined with innovative techniques such as growth factors, stem cell therapy, and distraction osteogenesis, provide effective solutions for restoring function and aesthetics. A multidisciplinary approach is essential to ensure comprehensive care and optimal results for these patients. |
| format | Article |
| id | doaj-art-cb98e89642fb44f68b3d58acbb65ec15 |
| institution | DOAJ |
| issn | 2227-9067 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Children |
| spelling | doaj-art-cb98e89642fb44f68b3d58acbb65ec152025-08-20T03:14:31ZengMDPI AGChildren2227-90672025-04-0112555910.3390/children12050559Options for Regenerative Treatment with Bone Grafts in Children with Anterior Lip/Palate Cleft—A ReviewAnna Miguel-Escribano0Cosimo Galletti1Juan de Quixano-Bardaji2Francisco Real-Voltas3Luca Fiorillo4Maria Cuevas-Nunez5Fulvia Galletti6Javier Flores-Fraile7Department of Integrated Dentistry, School of Dentistry, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallés, SpainSchool of Medicine and Surgery Kore, University of Enna, 94100 Enna, ItalyDepartment of Integrated Dentistry, School of Dentistry, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallés, SpainDepartment of Integrated Dentistry, School of Dentistry, Universitat Internacional de Catalunya, 08195 Sant Cugat del Vallés, SpainDepartment of Dental Cell Research, Dr. DY Patil Dental College and Hospital, Dr. DY Patil Vidyapeeth, Pune 411018, Maharashtra, IndiaDepartment of Biomedical and Dental Science and Morphological and Functional Imaging, University of Messina, 98166 Messina, ItalyDepartment of Biomedical and Dental Science and Morphological and Functional Imaging, University of Messina, 98166 Messina, ItalyDepartment of Surgery, Faculty of Medicine, University of Salamanca, 37007 Salamanca, SpainAnterior lip/palate cleft is a congenital deformity affecting the upper lip and palate, posing significant challenges in both aesthetic and functional aspects for children. Effective management of this condition is crucial for improving quality of life and ensuring normal development. This review aims to highlight the regenerative treatment options available for children with anterior lip/palate cleft, focusing on the use of bone grafts and other advanced dental procedures. A review of the current literature and clinical practices was conducted to identify and evaluate the most effective treatment options. Emphasis was placed on regenerative techniques, particularly the use of bone grafts. Advancements in regenerative dentistry offer promising outcomes for children with anterior lip/palate cleft. Bone grafts, combined with innovative techniques such as growth factors, stem cell therapy, and distraction osteogenesis, provide effective solutions for restoring function and aesthetics. A multidisciplinary approach is essential to ensure comprehensive care and optimal results for these patients.https://www.mdpi.com/2227-9067/12/5/559cleft lipcleft palateembryologyetiologyepidemiologybone graft |
| spellingShingle | Anna Miguel-Escribano Cosimo Galletti Juan de Quixano-Bardaji Francisco Real-Voltas Luca Fiorillo Maria Cuevas-Nunez Fulvia Galletti Javier Flores-Fraile Options for Regenerative Treatment with Bone Grafts in Children with Anterior Lip/Palate Cleft—A Review Children cleft lip cleft palate embryology etiology epidemiology bone graft |
| title | Options for Regenerative Treatment with Bone Grafts in Children with Anterior Lip/Palate Cleft—A Review |
| title_full | Options for Regenerative Treatment with Bone Grafts in Children with Anterior Lip/Palate Cleft—A Review |
| title_fullStr | Options for Regenerative Treatment with Bone Grafts in Children with Anterior Lip/Palate Cleft—A Review |
| title_full_unstemmed | Options for Regenerative Treatment with Bone Grafts in Children with Anterior Lip/Palate Cleft—A Review |
| title_short | Options for Regenerative Treatment with Bone Grafts in Children with Anterior Lip/Palate Cleft—A Review |
| title_sort | options for regenerative treatment with bone grafts in children with anterior lip palate cleft a review |
| topic | cleft lip cleft palate embryology etiology epidemiology bone graft |
| url | https://www.mdpi.com/2227-9067/12/5/559 |
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