Matrine disturbs the eimeria necatrix-induced loop of tuft cell-intestinal stem cell-goblet cell by inactivating IL-13/JAK2/STAT3 signaling
As sensors in the gut, tuft cells integrate a complex array of luminal signals to regulate the differentiation fate of intestinal stem cells (ISCs), which trigger a loop of tuft cell-ISC-goblet cell after parasitic infection. As a plant-derived alkaloid, Matrine plays a prominent role for standardiz...
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Main Authors: | Geng-xiu Zan, Hao-zhan Qu, Jia Meng, Xiao-fan Wang, Hui-chao Yan, Xiu-qi Wang, Jia-yi Zhou |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2025-02-01
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Series: | Poultry Science |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0032579125000239 |
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