Systematic analysis of the global, regional, and national burden of subarachnoid hemorrhage from 1990 to 2021.

Subarachnoid hemorrhage (SAH) is characterized by high rates of morbidity, mortality, and disability, which imposes a heavy disease burden on society and families. Incidence, mortality, disability-adjusted life years (DALYs) and their corresponding age-standardized rates (ASRs) and estimated annual...

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Main Authors: Wanyue Li, Huafei Yang, Furong Rui, Xinyi Ruan, Jun Xiong, Lin Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2025-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0323453
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author Wanyue Li
Huafei Yang
Furong Rui
Xinyi Ruan
Jun Xiong
Lin Chen
author_facet Wanyue Li
Huafei Yang
Furong Rui
Xinyi Ruan
Jun Xiong
Lin Chen
author_sort Wanyue Li
collection DOAJ
description Subarachnoid hemorrhage (SAH) is characterized by high rates of morbidity, mortality, and disability, which imposes a heavy disease burden on society and families. Incidence, mortality, disability-adjusted life years (DALYs) and their corresponding age-standardized rates (ASRs) and estimated annual percentage changes (EAPCs) of subarachnoid hemorrhage were analyzed by using GBD 2021 data in our study. Data were further stratified by age, sex, and region. Globally, in 2021, there were 697486 (95% UI, 614334795785) new cases of subarachnoid hemorrhage, 352,810 (309015401474) deaths, and 10.64 million (9.39 to 12.12) DALYs. The burden of subarachnoid hemorrhage showed substantial decline from 1990 to 2021. However, the decline in the age-standardized incidence rate was significantly smaller than the declines in the age-standardized mortality rate and age-standardized DALY rate, with the most pronounced downward trend in East Asia but an increase in sub-Saharan Africa, indicating that our prevention strategies require further refinement.
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spelling doaj-art-cb8ccce696ad498dad7283fe37d64f202025-08-20T02:23:15ZengPublic Library of Science (PLoS)PLoS ONE1932-62032025-01-01205e032345310.1371/journal.pone.0323453Systematic analysis of the global, regional, and national burden of subarachnoid hemorrhage from 1990 to 2021.Wanyue LiHuafei YangFurong RuiXinyi RuanJun XiongLin ChenSubarachnoid hemorrhage (SAH) is characterized by high rates of morbidity, mortality, and disability, which imposes a heavy disease burden on society and families. Incidence, mortality, disability-adjusted life years (DALYs) and their corresponding age-standardized rates (ASRs) and estimated annual percentage changes (EAPCs) of subarachnoid hemorrhage were analyzed by using GBD 2021 data in our study. Data were further stratified by age, sex, and region. Globally, in 2021, there were 697486 (95% UI, 614334795785) new cases of subarachnoid hemorrhage, 352,810 (309015401474) deaths, and 10.64 million (9.39 to 12.12) DALYs. The burden of subarachnoid hemorrhage showed substantial decline from 1990 to 2021. However, the decline in the age-standardized incidence rate was significantly smaller than the declines in the age-standardized mortality rate and age-standardized DALY rate, with the most pronounced downward trend in East Asia but an increase in sub-Saharan Africa, indicating that our prevention strategies require further refinement.https://doi.org/10.1371/journal.pone.0323453
spellingShingle Wanyue Li
Huafei Yang
Furong Rui
Xinyi Ruan
Jun Xiong
Lin Chen
Systematic analysis of the global, regional, and national burden of subarachnoid hemorrhage from 1990 to 2021.
PLoS ONE
title Systematic analysis of the global, regional, and national burden of subarachnoid hemorrhage from 1990 to 2021.
title_full Systematic analysis of the global, regional, and national burden of subarachnoid hemorrhage from 1990 to 2021.
title_fullStr Systematic analysis of the global, regional, and national burden of subarachnoid hemorrhage from 1990 to 2021.
title_full_unstemmed Systematic analysis of the global, regional, and national burden of subarachnoid hemorrhage from 1990 to 2021.
title_short Systematic analysis of the global, regional, and national burden of subarachnoid hemorrhage from 1990 to 2021.
title_sort systematic analysis of the global regional and national burden of subarachnoid hemorrhage from 1990 to 2021
url https://doi.org/10.1371/journal.pone.0323453
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