Hyperprogression disease induced by Sintilimab combined with Oxaliplatin and S-1 after surgery: a case report and literature review

Hyperprogression disease induced by Sintilimab combined with Oxaliplatin and S-1 after surgery: a case report and literature review

ObjectiveTo investigate the risk factors, underlying mechanisms, and preventive strategies associated with hyperprogressive disease (HPD) induced by immunotherapy.MethodsWe analyzed the clinical data of a patient who developed HPD following palliative gastrectomy and received a combination therapy o...

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Bibliographic Details
Main Authors: Yaoqi Li, You Wang, Rui Shen, Weijun Liu, Chenglou Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Oncology
Subjects:
gastric cancer
HPD
sintilimab
risk factors
mechanisms
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1494007/full
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