Repeatability and reproducibility of a new spectral-domain optical coherence tomography biometer and agreement with swept-source optical coherence tomography based biometer
Abstract Background To assess the repeatability and reproducibility of the Colombo IOL biometer (Moptim, China), which utilizes spectral-domain optical coherence tomography (SD-OCT), in measuring ocular parameters of normal subjects and to compare its agreement with the swept-source optical coherenc...
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BMC
2025-02-01
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| Series: | Eye and Vision |
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| Online Access: | https://doi.org/10.1186/s40662-024-00422-0 |
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| author | Xin Li Chak Seng Lei Rui Ning Luze Liu Aodong Chen Xinning Yang Giacomo Savini Domenico Schiano-Lomoriello Xingtao Zhou Jinhai Huang |
| author_facet | Xin Li Chak Seng Lei Rui Ning Luze Liu Aodong Chen Xinning Yang Giacomo Savini Domenico Schiano-Lomoriello Xingtao Zhou Jinhai Huang |
| author_sort | Xin Li |
| collection | DOAJ |
| description | Abstract Background To assess the repeatability and reproducibility of the Colombo IOL biometer (Moptim, China), which utilizes spectral-domain optical coherence tomography (SD-OCT), in measuring ocular parameters of normal subjects and to compare its agreement with the swept-source optical coherence tomography (SS-OCT)-based IOLMaster 700 biometer (Carl Zeiss Meditec AG, Germany). Methods This prospective study included 91 eyes from 91 normal subjects. The evaluated parameters were axial length (AL), central corneal thickness (CCT), aqueous depth (AQD), anterior chamber depth (ACD), lens thickness (LT), flattest and steepest meridian keratometry (Kf and Ks), mean keratometry (Km), astigmatism (AST) magnitude, white-to-white (WTW) distance, and pupil diameter (PD). The within-subject standard deviation (Sw), test–retest repeatability (TRT), coefficient of variation (CoV), and intraclass correlation coefficient (ICC) were calculated to determine the repeatability and reproducibility. Paired t-tests and Bland–Altman plots with 95% limits of agreement (LoA) were employed to assess the agreement. Results With respect to intraobserver repeatability, the Sw and TRT values of all evaluated parameters were low. Except J45 and PD, the ICCs were all higher than 0.928. The reproducibility Sw and TRT values of Colombo IOL were also low, and ICCs were not lower than 0.900. Comparing Colombo IOL and IOLMaster 700, the 95% LoA of AL, CCT, AQD, ACD, LT, Kf, Ks, Km, AST, J0, J45, WTW and PD ranged from − 0.08 to 0.03 mm, − 21.58 to 5.09 μm, 0.01 to 0.15 mm, − 0.01 to 0.14 mm, − 0.05 to 0.10 mm, − 0.14 to 0.59 D, − 0.31 to 0.40 D, − 0.13 to 0.40 D, − 0.68 to 0.32 D, − 0.09 to 0.34 D, − 0.07 to 0.25 D, 0.11 to 1.47 mm, and − 0.97 to 2.31 mm, respectively. Conclusion The new SD-OCT-based Colombo IOL biometer demonstrates excellent repeatability and reproducibility. Moreover, it generally agrees well with the SS-OCT-based IOLMaster 700, except for the WTW and PD measurements. |
| format | Article |
| id | doaj-art-cb764610a34043bb83dcc7ef4790fc53 |
| institution | Kabale University |
| issn | 2326-0254 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | BMC |
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| spelling | doaj-art-cb764610a34043bb83dcc7ef4790fc532025-02-02T12:08:59ZengBMCEye and Vision2326-02542025-02-0112111110.1186/s40662-024-00422-0Repeatability and reproducibility of a new spectral-domain optical coherence tomography biometer and agreement with swept-source optical coherence tomography based biometerXin Li0Chak Seng Lei1Rui Ning2Luze Liu3Aodong Chen4Xinning Yang5Giacomo Savini6Domenico Schiano-Lomoriello7Xingtao Zhou8Jinhai Huang9Eye Institute and Department of Ophthalmology and Vision Science, Eye & ENT Hospital, Fudan UniversityEye Institute and Department of Ophthalmology and Vision Science, Eye & ENT Hospital, Fudan UniversityEye Institute and Department of Ophthalmology and Vision Science, Eye & ENT Hospital, Fudan UniversityShanghai Research Center of Ophthalmology and OptometryEye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical UniversitySchool of Health Science and Engineering, University of Shanghai for Science and TechnologyG.B. Bietti Foundation I.R.C.C.SG.B. Bietti Foundation I.R.C.C.SEye Institute and Department of Ophthalmology and Vision Science, Eye & ENT Hospital, Fudan UniversityEye Institute and Department of Ophthalmology and Vision Science, Eye & ENT Hospital, Fudan UniversityAbstract Background To assess the repeatability and reproducibility of the Colombo IOL biometer (Moptim, China), which utilizes spectral-domain optical coherence tomography (SD-OCT), in measuring ocular parameters of normal subjects and to compare its agreement with the swept-source optical coherence tomography (SS-OCT)-based IOLMaster 700 biometer (Carl Zeiss Meditec AG, Germany). Methods This prospective study included 91 eyes from 91 normal subjects. The evaluated parameters were axial length (AL), central corneal thickness (CCT), aqueous depth (AQD), anterior chamber depth (ACD), lens thickness (LT), flattest and steepest meridian keratometry (Kf and Ks), mean keratometry (Km), astigmatism (AST) magnitude, white-to-white (WTW) distance, and pupil diameter (PD). The within-subject standard deviation (Sw), test–retest repeatability (TRT), coefficient of variation (CoV), and intraclass correlation coefficient (ICC) were calculated to determine the repeatability and reproducibility. Paired t-tests and Bland–Altman plots with 95% limits of agreement (LoA) were employed to assess the agreement. Results With respect to intraobserver repeatability, the Sw and TRT values of all evaluated parameters were low. Except J45 and PD, the ICCs were all higher than 0.928. The reproducibility Sw and TRT values of Colombo IOL were also low, and ICCs were not lower than 0.900. Comparing Colombo IOL and IOLMaster 700, the 95% LoA of AL, CCT, AQD, ACD, LT, Kf, Ks, Km, AST, J0, J45, WTW and PD ranged from − 0.08 to 0.03 mm, − 21.58 to 5.09 μm, 0.01 to 0.15 mm, − 0.01 to 0.14 mm, − 0.05 to 0.10 mm, − 0.14 to 0.59 D, − 0.31 to 0.40 D, − 0.13 to 0.40 D, − 0.68 to 0.32 D, − 0.09 to 0.34 D, − 0.07 to 0.25 D, 0.11 to 1.47 mm, and − 0.97 to 2.31 mm, respectively. Conclusion The new SD-OCT-based Colombo IOL biometer demonstrates excellent repeatability and reproducibility. Moreover, it generally agrees well with the SS-OCT-based IOLMaster 700, except for the WTW and PD measurements.https://doi.org/10.1186/s40662-024-00422-0Ocular biometryRepeatabilityReproducibilityAgreementOptical coherence tomography |
| spellingShingle | Xin Li Chak Seng Lei Rui Ning Luze Liu Aodong Chen Xinning Yang Giacomo Savini Domenico Schiano-Lomoriello Xingtao Zhou Jinhai Huang Repeatability and reproducibility of a new spectral-domain optical coherence tomography biometer and agreement with swept-source optical coherence tomography based biometer Eye and Vision Ocular biometry Repeatability Reproducibility Agreement Optical coherence tomography |
| title | Repeatability and reproducibility of a new spectral-domain optical coherence tomography biometer and agreement with swept-source optical coherence tomography based biometer |
| title_full | Repeatability and reproducibility of a new spectral-domain optical coherence tomography biometer and agreement with swept-source optical coherence tomography based biometer |
| title_fullStr | Repeatability and reproducibility of a new spectral-domain optical coherence tomography biometer and agreement with swept-source optical coherence tomography based biometer |
| title_full_unstemmed | Repeatability and reproducibility of a new spectral-domain optical coherence tomography biometer and agreement with swept-source optical coherence tomography based biometer |
| title_short | Repeatability and reproducibility of a new spectral-domain optical coherence tomography biometer and agreement with swept-source optical coherence tomography based biometer |
| title_sort | repeatability and reproducibility of a new spectral domain optical coherence tomography biometer and agreement with swept source optical coherence tomography based biometer |
| topic | Ocular biometry Repeatability Reproducibility Agreement Optical coherence tomography |
| url | https://doi.org/10.1186/s40662-024-00422-0 |
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