Chemical characterization of seaweed (Sargassum pallidum (turn.) C.Ag.) and kelp (Laminaria japonica Aresch.) from different origins by ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry

Seaweed (Sargassum pallidum (turn.) C.Ag.) and kelp (Laminaria japonica Aresch.) are two common marine plants, typical Chinese herbs with the same use as medicine and food. They are widely distributed in China and exhibit biological properties such as antioxidant, hypolipidemic, antitumor and hypogl...

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Main Authors: Nuo Xu, Qin Zhang, Yuman Li, Jinyang Shen, Di Zhang, Tuanjie Wang, Yun Shi, Kunming Qin
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:International Journal of Food Properties
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/10942912.2025.2471321
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author Nuo Xu
Qin Zhang
Yuman Li
Jinyang Shen
Di Zhang
Tuanjie Wang
Yun Shi
Kunming Qin
author_facet Nuo Xu
Qin Zhang
Yuman Li
Jinyang Shen
Di Zhang
Tuanjie Wang
Yun Shi
Kunming Qin
author_sort Nuo Xu
collection DOAJ
description Seaweed (Sargassum pallidum (turn.) C.Ag.) and kelp (Laminaria japonica Aresch.) are two common marine plants, typical Chinese herbs with the same use as medicine and food. They are widely distributed in China and exhibit biological properties such as antioxidant, hypolipidemic, antitumor and hypoglycemic effects. This study developed an ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS) method coupled with chemometric techniques to identify the chemical components in seaweed and kelp from different origins and examine the similarities and differences between the two herbs. A total of 48 constituents were identified, including fatty acids, alkaloids, terpenoids, amino acids, sterols, etc. For two compounds, Aurantiamide and Linoleic acid, the identification and fragmentation patterns were analyzed. Seaweed and kelp demonstrated a clear distinction. Principal component analysis, orthogonal partial least squares discriminant analysis, and cluster heatmap analysis were performed on seaweed and kelp. The seaweed samples were found to have high similarity and aggregation among different origins, while the kelp samples showed greater dispersion. Heatmap analysis further revealed the similarities and differences between seaweeds and kelp from different origins. This study provides a reliable foundation for the clinical application of the two herbs.
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publishDate 2025-12-01
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series International Journal of Food Properties
spelling doaj-art-cb75a7f210324aa09b5d7b27ccc26e462025-08-20T02:30:06ZengTaylor & Francis GroupInternational Journal of Food Properties1094-29121532-23862025-12-0128110.1080/10942912.2025.2471321Chemical characterization of seaweed (Sargassum pallidum (turn.) C.Ag.) and kelp (Laminaria japonica Aresch.) from different origins by ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometryNuo Xu0Qin Zhang1Yuman Li2Jinyang Shen3Di Zhang4Tuanjie Wang5Yun Shi6Kunming Qin7School of Pharmacy, Jiangsu Ocean University, Lianyungang, ChinaDepartment of Gastroenterology, Lianyungang Affiliated Hospital of Nanjing University of Chinese Medicine, Lianyungang, ChinaSchool of Pharmacy, Jiangsu Ocean University, Lianyungang, ChinaSchool of Pharmacy, Jiangsu Ocean University, Lianyungang, ChinaSchool of Pharmacy, Jiangsu Ocean University, Lianyungang, ChinaJiangsu Key Laboratory on Innovation for Marine Medicine and Modern Chinese Medicine, Lianyungang, ChinaSchool of Pharmacy, Jiangsu Ocean University, Lianyungang, ChinaSchool of Pharmacy, Jiangsu Ocean University, Lianyungang, ChinaSeaweed (Sargassum pallidum (turn.) C.Ag.) and kelp (Laminaria japonica Aresch.) are two common marine plants, typical Chinese herbs with the same use as medicine and food. They are widely distributed in China and exhibit biological properties such as antioxidant, hypolipidemic, antitumor and hypoglycemic effects. This study developed an ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry (UHPLC-Q-TOF-MS) method coupled with chemometric techniques to identify the chemical components in seaweed and kelp from different origins and examine the similarities and differences between the two herbs. A total of 48 constituents were identified, including fatty acids, alkaloids, terpenoids, amino acids, sterols, etc. For two compounds, Aurantiamide and Linoleic acid, the identification and fragmentation patterns were analyzed. Seaweed and kelp demonstrated a clear distinction. Principal component analysis, orthogonal partial least squares discriminant analysis, and cluster heatmap analysis were performed on seaweed and kelp. The seaweed samples were found to have high similarity and aggregation among different origins, while the kelp samples showed greater dispersion. Heatmap analysis further revealed the similarities and differences between seaweeds and kelp from different origins. This study provides a reliable foundation for the clinical application of the two herbs.https://www.tandfonline.com/doi/10.1080/10942912.2025.2471321UHPLC-Q-TOF-MSSeaweedKelpPCAOPLS-D
spellingShingle Nuo Xu
Qin Zhang
Yuman Li
Jinyang Shen
Di Zhang
Tuanjie Wang
Yun Shi
Kunming Qin
Chemical characterization of seaweed (Sargassum pallidum (turn.) C.Ag.) and kelp (Laminaria japonica Aresch.) from different origins by ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry
International Journal of Food Properties
UHPLC-Q-TOF-MS
Seaweed
Kelp
PCA
OPLS-D
title Chemical characterization of seaweed (Sargassum pallidum (turn.) C.Ag.) and kelp (Laminaria japonica Aresch.) from different origins by ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry
title_full Chemical characterization of seaweed (Sargassum pallidum (turn.) C.Ag.) and kelp (Laminaria japonica Aresch.) from different origins by ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry
title_fullStr Chemical characterization of seaweed (Sargassum pallidum (turn.) C.Ag.) and kelp (Laminaria japonica Aresch.) from different origins by ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry
title_full_unstemmed Chemical characterization of seaweed (Sargassum pallidum (turn.) C.Ag.) and kelp (Laminaria japonica Aresch.) from different origins by ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry
title_short Chemical characterization of seaweed (Sargassum pallidum (turn.) C.Ag.) and kelp (Laminaria japonica Aresch.) from different origins by ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry
title_sort chemical characterization of seaweed sargassum pallidum turn c ag and kelp laminaria japonica aresch from different origins by ultra high performance liquid chromatography quadrupole time of flight mass spectrometry
topic UHPLC-Q-TOF-MS
Seaweed
Kelp
PCA
OPLS-D
url https://www.tandfonline.com/doi/10.1080/10942912.2025.2471321
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