Validation of Biomarkers and Immunotherapy With Crohn’s Disease Using WGCNA and Two-Sample Mendelian Randomization Study

Validation of Biomarkers and Immunotherapy With Crohn’s Disease Using WGCNA and Two-Sample Mendelian Randomization Study

Conclusions: The study screened five potential biomarker genes in CD patients using a bioinformatics approach and Mendelian randomization study. Our results provided insights into CXCL1, LCN2, NOS2, S100A8, and DUOX2 in CD and suggested that CXCL1 may potentially be the optimal biomarker that could...

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Bibliographic Details
Main Authors: Cong Hu, Shuxiong Nong, Chenang Liu, Yongfeng Chen, Chilin Liao, Meng Wu
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/grp/8194480
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