Cardiovascular Effects of Metformin
Type 2 diabetes mellitus is one of the most important independent risk factors for the development, progression and mortality from cardiovascular diseases (CVD). The world communities are faced with the question of developing the optimal management tactics for such comorbidity patients. Thus, the pr...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Столичная издательская компания
2022-03-01
|
| Series: | Рациональная фармакотерапия в кардиологии |
| Subjects: | |
| Online Access: | https://www.rpcardio.online/jour/article/view/2664 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849227605088141312 |
|---|---|
| author | B. T. Kurmanbekova A. M. Noruizbaeva |
| author_facet | B. T. Kurmanbekova A. M. Noruizbaeva |
| author_sort | B. T. Kurmanbekova |
| collection | DOAJ |
| description | Type 2 diabetes mellitus is one of the most important independent risk factors for the development, progression and mortality from cardiovascular diseases (CVD). The world communities are faced with the question of developing the optimal management tactics for such comorbidity patients. Thus, the prescribed drug should not only have an adequate hypoglycemic effect, but also have a number of cardioprotective properties, be safe in patients with CVD, and possibly even improve the prognosis and reduce mortality rates. This review is devoted to a representative of the biguanide class - metformin, which is one of the earliest and most effective antihyperglycemic drugs, both as monotherapy and in combination with other antihyperglycemic drugs and insulin; while the evidence base for its cardiovascular profile is only gaining momentum. Thus, the purpose of this review is to highlight the cardiovascular effects of metformin in the context of recent research. |
| format | Article |
| id | doaj-art-cb704deeeb204c88a5f33fbdcf7cfded |
| institution | Kabale University |
| issn | 1819-6446 2225-3653 |
| language | English |
| publishDate | 2022-03-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj-art-cb704deeeb204c88a5f33fbdcf7cfded2025-08-23T10:00:34ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532022-03-011819710210.20996/1819-6446-2022-02-121981Cardiovascular Effects of MetforminB. T. Kurmanbekova0A. M. Noruizbaeva1National Center of cardiology and internal medicine named after academician M.MirrakhimovNational Center of cardiology and internal medicine named after academician M.MirrakhimovType 2 diabetes mellitus is one of the most important independent risk factors for the development, progression and mortality from cardiovascular diseases (CVD). The world communities are faced with the question of developing the optimal management tactics for such comorbidity patients. Thus, the prescribed drug should not only have an adequate hypoglycemic effect, but also have a number of cardioprotective properties, be safe in patients with CVD, and possibly even improve the prognosis and reduce mortality rates. This review is devoted to a representative of the biguanide class - metformin, which is one of the earliest and most effective antihyperglycemic drugs, both as monotherapy and in combination with other antihyperglycemic drugs and insulin; while the evidence base for its cardiovascular profile is only gaining momentum. Thus, the purpose of this review is to highlight the cardiovascular effects of metformin in the context of recent research.https://www.rpcardio.online/jour/article/view/2664metformincardiovascular diseasecardioprotective properties |
| spellingShingle | B. T. Kurmanbekova A. M. Noruizbaeva Cardiovascular Effects of Metformin Рациональная фармакотерапия в кардиологии metformin cardiovascular disease cardioprotective properties |
| title | Cardiovascular Effects of Metformin |
| title_full | Cardiovascular Effects of Metformin |
| title_fullStr | Cardiovascular Effects of Metformin |
| title_full_unstemmed | Cardiovascular Effects of Metformin |
| title_short | Cardiovascular Effects of Metformin |
| title_sort | cardiovascular effects of metformin |
| topic | metformin cardiovascular disease cardioprotective properties |
| url | https://www.rpcardio.online/jour/article/view/2664 |
| work_keys_str_mv | AT btkurmanbekova cardiovasculareffectsofmetformin AT amnoruizbaeva cardiovasculareffectsofmetformin |