Unveiling the molecular blueprint of SKP-SCs-mediated tissue engineering-enhanced neuroregeneration

Unveiling the molecular blueprint of SKP-SCs-mediated tissue engineering-enhanced neuroregeneration

Abstract Peripheral nerve injury poses a significant challenge to the nervous system’s regenerative capacity. We previously described a novel approach to construct a chitosan/silk fibroin nerve graft with skin-derived precursor-induced Schwann cells (SKP-SCs). This graft has been shown to promote sc...

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Bibliographic Details
Main Authors: Hui Zhu, Ying Wang, Siyuan Xu, Yunjian Song, Yifan Li, Yiting Wang, Qiuwen Sun, Muyuan Tong, Tianyi Huang, Yulin Pan, Hongkui Wang, Xi Xu, Chengbin Xue
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Nanobiotechnology
Subjects:
Tissue engineering
Peripheral nerve regeneration
Sciatic nerve injury
Schwann cells
Skin-derived precursors
Weighted gene co-expression network analysis (WGCNA)
Online Access:https://doi.org/10.1186/s12951-024-03076-1
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