Tryptophan metabolic reprogramming modulates cytokine networks in nucleos(t)ide analogue-treated chronic hepatitis B patients

Tryptophan metabolic reprogramming modulates cytokine networks in nucleos(t)ide analogue-treated chronic hepatitis B patients

Background & aimsHepatitis B virus (HBV) infection remains a global health challenge. Tryptophan metabolism influences immune regulation, but its interplay with cytokines during antiviral therapy is unclear. We investigated associations between tryptophan pathways and cytokine profiles in th...

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Bibliographic Details
Main Authors: Xuedan Gao, Xiaojuan Wu, Yi Li, Xinhua Dai, Bei Cai
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
tryptophan metabolism
cytokine profiles
chronic hepatitis B
bacterial degradation pathway
functional cure
indole-3-carboxaldehyde
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2025.1643636/full
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