Preventive role of rottlerin in endotoxin-induced uveitic glaucoma in rats

Preventive role of rottlerin in endotoxin-induced uveitic glaucoma in rats

Abstract Background Rottlerin is a natural polyphenolic compound obtained from dried ripe fruits of Mallotus philippinensis and is primarily used as a PKCδ inhibitor. The effectiveness of rottlerin was checked in the endotoxin-induced glaucoma models, focusing on its impact on intraocular pressure,...

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Bibliographic Details
Main Authors: Nidhi Kumari, Ashmita Das, Nirdesh Kumar, Geeta Singh, Urvashi Jain, Amrita Singh, Surendra H. Bodakhe
Format: Article
Language:English
Published: SpringerOpen 2025-04-01
Series:Future Journal of Pharmaceutical Sciences
Subjects:
Rottlerin
PKCδ inhibitor
LPS
Inflammation
Anti-oxidants
Uveitic glaucoma
Online Access:https://doi.org/10.1186/s43094-025-00798-3
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