The SARS-CoV-2 main protease causes mitochondrial dysfunction in a yeast model

The SARS-CoV-2 main protease causes mitochondrial dysfunction in a yeast model

Abstract Saccharomyces cerevisiae has proven to be an invaluable model organism for studying mitochondrial function owing to its genetic tractability and the high conservation of mitochondrial processes among eukaryotes, including humans. Yeasts are easy to culture and manipulate genetically, which...

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Main Authors: Wojciech Grabiński, Anna Kicińska, Karolina Funtowicz, Tomasz Skrzypczak, Andonis Karachitos
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-11993-w
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