Effect of continuous nursing on neutrophil gelatinase-associated lipocalin in patients with lupus nephritis

Objective To investigate the influence of continuous nursing on serum creatinine(SCr)and blood urea nitrogen(BUN),serum and urinary neutrophil gelatinase-associated lipocalin(NGAL)level in patients with lupus nephritis(LN).Methods Sixty cases of LN were randomly divided into 2 groups:control group(r...

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Main Authors: ZHANG Xian-qin, SHEN Ting, XIE Xiao-hang, ZOU Rong
Format: Article
Language:zho
Published: Editorial Department of Journal of Clinical Nephrology 2018-01-01
Series:Linchuang shenzangbing zazhi
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Online Access:http://www.lcszb.com/thesisDetails?columnId=57914050&Fpath=home&index=0
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author ZHANG Xian-qin
SHEN Ting
XIE Xiao-hang
ZOU Rong
author_facet ZHANG Xian-qin
SHEN Ting
XIE Xiao-hang
ZOU Rong
author_sort ZHANG Xian-qin
collection DOAJ
description Objective To investigate the influence of continuous nursing on serum creatinine(SCr)and blood urea nitrogen(BUN),serum and urinary neutrophil gelatinase-associated lipocalin(NGAL)level in patients with lupus nephritis(LN).Methods Sixty cases of LN were randomly divided into 2 groups:control group(routine nursing)and observation group(continuous nursing).Levels of SCr and BUN in serum,serum and urinary NGAL were measured by ELISA at discharge and 6 months after hospital discharge.Results At 6 th month after discharge,serum SCr and BUN,serum and urinary NGAL had no significant elevation in observation group as compared with those at discharge,and significantly reduced in observation group as compared with those in control group(P<0.05).The satisfaction in observation group was significantly higher than that in control group(93.3%vs.60.0%,P<0.05).Urinary NGAL was closely correlated with LN.Conclusions Continuous nursing intervention can control SCr,BUN and NGAL levels in patients with LN after the symptoms are stable and discharged.Continuous nursing can slow the progression of the disease,and improve the degree of patient’s satisfaction,which is worth further promotion in the clinical practice.
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publishDate 2018-01-01
publisher Editorial Department of Journal of Clinical Nephrology
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series Linchuang shenzangbing zazhi
spelling doaj-art-cb58a86f0e4a446aa3add8b7deb94ab22025-08-20T03:52:51ZzhoEditorial Department of Journal of Clinical NephrologyLinchuang shenzangbing zazhi1671-23902018-01-0176176457914050Effect of continuous nursing on neutrophil gelatinase-associated lipocalin in patients with lupus nephritisZHANG Xian-qinSHEN TingXIE Xiao-hangZOU RongObjective To investigate the influence of continuous nursing on serum creatinine(SCr)and blood urea nitrogen(BUN),serum and urinary neutrophil gelatinase-associated lipocalin(NGAL)level in patients with lupus nephritis(LN).Methods Sixty cases of LN were randomly divided into 2 groups:control group(routine nursing)and observation group(continuous nursing).Levels of SCr and BUN in serum,serum and urinary NGAL were measured by ELISA at discharge and 6 months after hospital discharge.Results At 6 th month after discharge,serum SCr and BUN,serum and urinary NGAL had no significant elevation in observation group as compared with those at discharge,and significantly reduced in observation group as compared with those in control group(P<0.05).The satisfaction in observation group was significantly higher than that in control group(93.3%vs.60.0%,P<0.05).Urinary NGAL was closely correlated with LN.Conclusions Continuous nursing intervention can control SCr,BUN and NGAL levels in patients with LN after the symptoms are stable and discharged.Continuous nursing can slow the progression of the disease,and improve the degree of patient’s satisfaction,which is worth further promotion in the clinical practice.http://www.lcszb.com/thesisDetails?columnId=57914050&Fpath=home&index=0Continuous nursingLupus nephritisSerum creatinineBlood urea nitrogenNeutrophil gelatinase-associated lipocalin
spellingShingle ZHANG Xian-qin
SHEN Ting
XIE Xiao-hang
ZOU Rong
Effect of continuous nursing on neutrophil gelatinase-associated lipocalin in patients with lupus nephritis
Linchuang shenzangbing zazhi
Continuous nursing
Lupus nephritis
Serum creatinine
Blood urea nitrogen
Neutrophil gelatinase-associated lipocalin
title Effect of continuous nursing on neutrophil gelatinase-associated lipocalin in patients with lupus nephritis
title_full Effect of continuous nursing on neutrophil gelatinase-associated lipocalin in patients with lupus nephritis
title_fullStr Effect of continuous nursing on neutrophil gelatinase-associated lipocalin in patients with lupus nephritis
title_full_unstemmed Effect of continuous nursing on neutrophil gelatinase-associated lipocalin in patients with lupus nephritis
title_short Effect of continuous nursing on neutrophil gelatinase-associated lipocalin in patients with lupus nephritis
title_sort effect of continuous nursing on neutrophil gelatinase associated lipocalin in patients with lupus nephritis
topic Continuous nursing
Lupus nephritis
Serum creatinine
Blood urea nitrogen
Neutrophil gelatinase-associated lipocalin
url http://www.lcszb.com/thesisDetails?columnId=57914050&Fpath=home&index=0
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AT xiexiaohang effectofcontinuousnursingonneutrophilgelatinaseassociatedlipocalininpatientswithlupusnephritis
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