Association of Plasma KIM-1, TNFR-1, and TNFR-2 With Cardiovascular Outcomes and All-Cause Mortality in Individuals With Chronic Kidney Disease: An Ancillary Analysis of SPRINT

Association of Plasma KIM-1, TNFR-1, and TNFR-2 With Cardiovascular Outcomes and All-Cause Mortality in Individuals With Chronic Kidney Disease: An Ancillary Analysis of SPRINT

Rationale & Objective: Among individuals with chronic kidney disease (CKD), higher blood levels of kidney injury molecule-1 (KIM-1) and soluble tumor necrosis factor receptors (TNFR-1 and TNFR-2) have been associated with greater risk of CKD progression. Their associations with risk of cardi...

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Bibliographic Details
Main Authors: Nicholas Wettersten, Ronit Katz, Simon B. Ascher, Rebecca Scherzer, Alexander L. Bullen, Teresa K. Chen, Kasey Campos, Pranav S. Garimella, Michelle M. Estrella, Michael G. Shlipak, Joachim H. Ix
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Kidney Medicine
Subjects:
Inflammation
kidney injury
mortality
cardiovascular risk
chronic kidney disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2590059525000603
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