Effect of SkQ1 Antioxidant on Structural and Functional Conditions of The Brain in PostResuscitation Period
The aim was to assess the efficacy of mitochondriatargeted antioxidant SkQ1 in prevention of structural and functional abnormalities of brain postresuscitation after cardiac arrest.Materials and methods. Adult male Wistar rats (n=19) underwent cardiac arrest for 7 minutes followed by resuscitation....
Saved in:
| Main Authors: | M. L. Lovat, M. Sh. Avrushchenko, O. A. Averina, V. V. Pavshintsev, I. V. Ostrova, Y. V. Zarzhetsky, V. V. Moroz, M. V. Egorov |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology, Moscow, Russia
2016-07-01
|
| Series: | Общая реаниматология |
| Subjects: | |
| Online Access: | https://www.reanimatology.com/rmt/article/view/1517 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Antioxidant Effect of Mitochondrially Targeted Antioxidant SkQ1 on the Isolated Rat Heart Model
by: E. A. Senokosova, et al.
Published: (2022-08-01) -
Postresuscitation Changes in the Expression of GlialDerived Neurotrophic Factor (GDNF): Association with Cerebellar Purkinje Cell Damage (An experimental study)
by: M. Sh. Avrushchenko, et al.
Published: (2014-10-01) -
Two-faced Janus SkQ1/SkQR1: patterns and molecular volume threshold for substrate recognition by the AcrAB-TolC pump
by: Marina V. Karakozova, et al.
Published: (2025-03-01) -
Analysis of mitochondrial-targeted antioxidant SkQ1 effectiveness on myocardial ischemia-reperfusion injury in a rat model: Focus on morphological and ultrastructural tissue study
by: E. A. Senokosova, et al.
Published: (2025-03-01) -
Postresuscitative Changes in the Morphofunctional State of Nerve Cells: Implication in the Pathogenesis of Encephalopathies
by: M. Sh. Avrushchenko, et al.
Published: (2006-12-01)