Recent Advances of Fluorescent Aptasensors for the Detection of Antibiotics in Food

Antibiotics can accumulate in the body via ingestion, presenting serious health and safety risks to humans, and have garnered extensive international attention in recent years. Meanwhile, aptamers have been applied in the detection of antibiotics, mainly because of their good stability, high specifi...

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Main Authors: Zheng Liu, Wenyi Yang, Huikai Lin, Mingdi Zhang, Chunyan Sun
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Biosensors
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Online Access:https://www.mdpi.com/2079-6374/15/4/252
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author Zheng Liu
Wenyi Yang
Huikai Lin
Mingdi Zhang
Chunyan Sun
author_facet Zheng Liu
Wenyi Yang
Huikai Lin
Mingdi Zhang
Chunyan Sun
author_sort Zheng Liu
collection DOAJ
description Antibiotics can accumulate in the body via ingestion, presenting serious health and safety risks to humans, and have garnered extensive international attention in recent years. Meanwhile, aptamers have been applied in the detection of antibiotics, mainly because of their good stability, high specificity, easy synthesis, and low cost. Among various kinds of aptasensors, fluorescent dye-based or nanomaterial-based fluorescent aptasensors serve as highly efficient tools for the rapid quantification of antibiotics owing to their remarkable sensitivity, specificity, and selectivity. In addition, some novel techniques such as aptamer tailoring, signal amplification, and artificial intelligence for aptasensors are also presented. This paper provides a detailed and comprehensive review of fluorescent aptasensors for antibiotic detection. Moreover, it pinpoints the challenges encountered during the development of the aforesaid fluorescent aptasensors and puts forward future research directions.
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spelling doaj-art-cb46437573094b6c982c52b47c6efa2e2025-08-20T03:14:27ZengMDPI AGBiosensors2079-63742025-04-0115425210.3390/bios15040252Recent Advances of Fluorescent Aptasensors for the Detection of Antibiotics in FoodZheng Liu0Wenyi Yang1Huikai Lin2Mingdi Zhang3Chunyan Sun4Department of Food Quality and Safety, Jilin University, Changchun 130062, ChinaDepartment of Food Quality and Safety, Jilin University, Changchun 130062, ChinaDepartment of Food Quality and Safety, Jilin University, Changchun 130062, ChinaDepartment of Food Quality and Safety, Jilin University, Changchun 130062, ChinaDepartment of Food Quality and Safety, Jilin University, Changchun 130062, ChinaAntibiotics can accumulate in the body via ingestion, presenting serious health and safety risks to humans, and have garnered extensive international attention in recent years. Meanwhile, aptamers have been applied in the detection of antibiotics, mainly because of their good stability, high specificity, easy synthesis, and low cost. Among various kinds of aptasensors, fluorescent dye-based or nanomaterial-based fluorescent aptasensors serve as highly efficient tools for the rapid quantification of antibiotics owing to their remarkable sensitivity, specificity, and selectivity. In addition, some novel techniques such as aptamer tailoring, signal amplification, and artificial intelligence for aptasensors are also presented. This paper provides a detailed and comprehensive review of fluorescent aptasensors for antibiotic detection. Moreover, it pinpoints the challenges encountered during the development of the aforesaid fluorescent aptasensors and puts forward future research directions.https://www.mdpi.com/2079-6374/15/4/252fluorescentaptasensorsdyesnanomaterialsantibioticsfood
spellingShingle Zheng Liu
Wenyi Yang
Huikai Lin
Mingdi Zhang
Chunyan Sun
Recent Advances of Fluorescent Aptasensors for the Detection of Antibiotics in Food
Biosensors
fluorescent
aptasensors
dyes
nanomaterials
antibiotics
food
title Recent Advances of Fluorescent Aptasensors for the Detection of Antibiotics in Food
title_full Recent Advances of Fluorescent Aptasensors for the Detection of Antibiotics in Food
title_fullStr Recent Advances of Fluorescent Aptasensors for the Detection of Antibiotics in Food
title_full_unstemmed Recent Advances of Fluorescent Aptasensors for the Detection of Antibiotics in Food
title_short Recent Advances of Fluorescent Aptasensors for the Detection of Antibiotics in Food
title_sort recent advances of fluorescent aptasensors for the detection of antibiotics in food
topic fluorescent
aptasensors
dyes
nanomaterials
antibiotics
food
url https://www.mdpi.com/2079-6374/15/4/252
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