GNG2 inhibits brain metastases from colorectal cancer via PI3K/AKT/mTOR signaling pathway
Abstract G-protein gamma subunit 2 (GNG2) plays a vital role in various cellular processes, yet its specific function in colorectal cancer (CRC), particularly in highly invasive cases and brain metastasis, remains unclear. This study identifies GNG2 as a key regulator in metastatic colorectal cancer...
Saved in:
| Main Authors: | Chenhua Luo, ZhiMing Xiao, WenLong Yang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-01-01
|
| Series: | Scientific Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1038/s41598-025-85592-0 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Emerging Role and Clinical Significance of PI3K-Akt-mTOR in Rhabdomyosarcoma
by: Ilaria Versari, et al.
Published: (2025-02-01) -
Research on the role and mechanism of the PI3K/Akt/mTOR signalling pathway in osteoporosis
by: Chuanlong Liu, et al.
Published: (2025-05-01) -
Assessments of prostate cancer cell functions highlight differences between a pan‐PI3K/mTOR inhibitor, gedatolisib, and single‐node inhibitors of the PI3K/AKT/mTOR pathway
by: Adrish Sen, et al.
Published: (2025-01-01) -
Synergistic Antitumor Effects of Ivermectin and Metformin in Canine Breast Cancer via PI3K/AKT/mTOR Pathway Inhibition
by: Huili Feng, et al.
Published: (2025-05-01) -
Sparstolonin B Reduces Estrogen-Dependent Proliferation in Cancer Cells: Possible Role of Ceramide and PI3K/AKT/mTOR Inhibition
by: Yağmur Dilber, et al.
Published: (2024-11-01)