Research on the Control Method of Feeding Microenvironment of Individually Ventilated Mouse Cages in Barrier Environment
The air-conditioning system of an independent ventilation cage (IVC) often controls the cage-level and room-level environments. However, compared with the room-level macroenvironment, the surrounding environment of laboratory animals, known as the animal feeding microenvironment, plays a key role in...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | zho |
| Published: |
Journal of Refrigeration Magazines Agency Co., Ltd.
2022-01-01
|
| Series: | Zhileng xuebao |
| Subjects: | |
| Online Access: | http://www.zhilengxuebao.com/thesisDetails#10.3969/j.issn.0253-4339.2022.06.090 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849707603395870720 |
|---|---|
| author | Gong Guangcai He Xizhi Chen Mengjun Chen Xiang Peng Pei Yu Wangyi |
| author_facet | Gong Guangcai He Xizhi Chen Mengjun Chen Xiang Peng Pei Yu Wangyi |
| author_sort | Gong Guangcai |
| collection | DOAJ |
| description | The air-conditioning system of an independent ventilation cage (IVC) often controls the cage-level and room-level environments. However, compared with the room-level macroenvironment, the surrounding environment of laboratory animals, known as the animal feeding microenvironment, plays a key role in improving their welfare. To optimize the control method of the feeding microenvironment and the performance of the IVC air-conditioning system, a heat transfer model was established and the IVC mouse feeding microenvironment was simulated using computational fluid dynamics models. The microenvironment and macroenvironment parameters were also measured experimentally. The results demonstrate differences between the IVC mouse feeding microenvironment and macroenvironment parameters. The air supply speed in the IVCs at different locations in the same cabinet ranged from 2.79 to 4.94 m/s, which changed the velocity field in the cage. At supply air speeds of 2.97 and 4.94 m/s, the average wind speed at the inlet side was 54.7% and 60.4% higher than that at the outlet side, respectively. When the air supply speed reached 4.94 m/s, the wind speed behind the mouse exceeded 0.3 m/s, which is beyond the specified limit. The velocity field also affected the temperature, humidity, and pollutant concentration distribution. These results demonstrate that the IVC air-conditioning system should be designed based on cages with the worst hydraulic balance to improve the feeding microenvironment and ensure the welfare and quality of laboratory animals. |
| format | Article |
| id | doaj-art-cb3b33d52fbf4a91b191cf7ce05dce10 |
| institution | DOAJ |
| issn | 0253-4339 |
| language | zho |
| publishDate | 2022-01-01 |
| publisher | Journal of Refrigeration Magazines Agency Co., Ltd. |
| record_format | Article |
| series | Zhileng xuebao |
| spelling | doaj-art-cb3b33d52fbf4a91b191cf7ce05dce102025-08-20T03:15:53ZzhoJournal of Refrigeration Magazines Agency Co., Ltd.Zhileng xuebao0253-43392022-01-014366500870Research on the Control Method of Feeding Microenvironment of Individually Ventilated Mouse Cages in Barrier EnvironmentGong GuangcaiHe XizhiChen MengjunChen XiangPeng PeiYu WangyiThe air-conditioning system of an independent ventilation cage (IVC) often controls the cage-level and room-level environments. However, compared with the room-level macroenvironment, the surrounding environment of laboratory animals, known as the animal feeding microenvironment, plays a key role in improving their welfare. To optimize the control method of the feeding microenvironment and the performance of the IVC air-conditioning system, a heat transfer model was established and the IVC mouse feeding microenvironment was simulated using computational fluid dynamics models. The microenvironment and macroenvironment parameters were also measured experimentally. The results demonstrate differences between the IVC mouse feeding microenvironment and macroenvironment parameters. The air supply speed in the IVCs at different locations in the same cabinet ranged from 2.79 to 4.94 m/s, which changed the velocity field in the cage. At supply air speeds of 2.97 and 4.94 m/s, the average wind speed at the inlet side was 54.7% and 60.4% higher than that at the outlet side, respectively. When the air supply speed reached 4.94 m/s, the wind speed behind the mouse exceeded 0.3 m/s, which is beyond the specified limit. The velocity field also affected the temperature, humidity, and pollutant concentration distribution. These results demonstrate that the IVC air-conditioning system should be designed based on cages with the worst hydraulic balance to improve the feeding microenvironment and ensure the welfare and quality of laboratory animals.http://www.zhilengxuebao.com/thesisDetails#10.3969/j.issn.0253-4339.2022.06.090IVCfeeding microenvironmentcontrol methodlaboratory animal welfare |
| spellingShingle | Gong Guangcai He Xizhi Chen Mengjun Chen Xiang Peng Pei Yu Wangyi Research on the Control Method of Feeding Microenvironment of Individually Ventilated Mouse Cages in Barrier Environment Zhileng xuebao IVC feeding microenvironment control method laboratory animal welfare |
| title | Research on the Control Method of Feeding Microenvironment of Individually Ventilated Mouse Cages in Barrier Environment |
| title_full | Research on the Control Method of Feeding Microenvironment of Individually Ventilated Mouse Cages in Barrier Environment |
| title_fullStr | Research on the Control Method of Feeding Microenvironment of Individually Ventilated Mouse Cages in Barrier Environment |
| title_full_unstemmed | Research on the Control Method of Feeding Microenvironment of Individually Ventilated Mouse Cages in Barrier Environment |
| title_short | Research on the Control Method of Feeding Microenvironment of Individually Ventilated Mouse Cages in Barrier Environment |
| title_sort | research on the control method of feeding microenvironment of individually ventilated mouse cages in barrier environment |
| topic | IVC feeding microenvironment control method laboratory animal welfare |
| url | http://www.zhilengxuebao.com/thesisDetails#10.3969/j.issn.0253-4339.2022.06.090 |
| work_keys_str_mv | AT gongguangcai researchonthecontrolmethodoffeedingmicroenvironmentofindividuallyventilatedmousecagesinbarrierenvironment AT hexizhi researchonthecontrolmethodoffeedingmicroenvironmentofindividuallyventilatedmousecagesinbarrierenvironment AT chenmengjun researchonthecontrolmethodoffeedingmicroenvironmentofindividuallyventilatedmousecagesinbarrierenvironment AT chenxiang researchonthecontrolmethodoffeedingmicroenvironmentofindividuallyventilatedmousecagesinbarrierenvironment AT pengpei researchonthecontrolmethodoffeedingmicroenvironmentofindividuallyventilatedmousecagesinbarrierenvironment AT yuwangyi researchonthecontrolmethodoffeedingmicroenvironmentofindividuallyventilatedmousecagesinbarrierenvironment |