Dose sensitivity of MAGIC-f polymer gel using different MRI sequences
This study aims to evaluate the dose sensitivity of MAGIC-f gel irradiated by high-energy photon beams, comparing quantification using different MRI sequences. Irradiation was performed using 6 MV photons with 600 cGy/min dose rate, field size of 20x20 cm², and 94 cm source-to-surface distance. Two...
Saved in:
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)
2022-12-01
|
| Series: | Brazilian Journal of Radiation Sciences |
| Subjects: | |
| Online Access: | https://bjrs.org.br/revista/index.php/REVISTA/article/view/2085 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849715978973216768 |
|---|---|
| author | Nícollas Gonçalves Cavedini Ricardo Meurer Papaléo Nícolas Borges Jobim Phelipi Nunes Schuck Fabrício Nery Garrafiel Elisa Magno Nunes de Oliveira Marcelo Menna Barreto Schwarcke Alex Cristóvão Holanda de Oliveira Paulo Rauli Rafeson Vasconcelos Caribé Ana Maria Marques da Silva |
| author_facet | Nícollas Gonçalves Cavedini Ricardo Meurer Papaléo Nícolas Borges Jobim Phelipi Nunes Schuck Fabrício Nery Garrafiel Elisa Magno Nunes de Oliveira Marcelo Menna Barreto Schwarcke Alex Cristóvão Holanda de Oliveira Paulo Rauli Rafeson Vasconcelos Caribé Ana Maria Marques da Silva |
| author_sort | Nícollas Gonçalves Cavedini |
| collection | DOAJ |
| description | This study aims to evaluate the dose sensitivity of MAGIC-f gel irradiated by high-energy photon beams, comparing quantification using different MRI sequences. Irradiation was performed using 6 MV photons with 600 cGy/min dose rate, field size of 20x20 cm², and 94 cm source-to-surface distance. Two gel batches were produced on different days and placed in vials. In the first batch, doses of 0, 2, 4, 6, 8, 10, 20, and 40 Gy were planned. The second batch was irradiated with doses of 0, 2, 4, 6, 10, 12, 14, and 16 Gy. MR images were acquired with Spin Echo (SE, TR=3 s) and Multi Spin Echo (MSE, TR = 3s or 10s, turbo factor 24) sequences. The dose is assessed via changes in the transverse relaxation time in the irradiated gel. In MSE, dose sensitivity in the first batch was 0.27 (TR=3 s) and 0.28 Gy-1s-1 (TR=10 s) and in the second batch, 0.31 and 0.31 Gy-1s-1 (TR = 3 s and TR = 10 s, respectively). In the SE sequence, dose sensitivity was 0.42 for the first batch and 0.43 Gy-1s-1 for the second batch. Linearity of dose-response was only obtained for doses below 10 Gy. Comparing the dose sensitivity extracted from MSE and SE sequences using TR= 3s, differences around 30% were found. Thus, although MSE-MRI offers a faster protocol of imaging acquisition it is less precise for quantification of relaxation times, as TE is not a well-defined quantity. The performance of the gel as a dosimeter is consequently sequence dependent. |
| format | Article |
| id | doaj-art-cb2ced43111444fdb0b288dd4dfacde1 |
| institution | DOAJ |
| issn | 2319-0612 |
| language | English |
| publishDate | 2022-12-01 |
| publisher | Brazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR) |
| record_format | Article |
| series | Brazilian Journal of Radiation Sciences |
| spelling | doaj-art-cb2ced43111444fdb0b288dd4dfacde12025-08-20T03:13:10ZengBrazilian Radiation Protection Society (Sociedade Brasileira de Proteção Radiológica, SBPR)Brazilian Journal of Radiation Sciences2319-06122022-12-0110411510.15392/2319-0612.2022.20851703Dose sensitivity of MAGIC-f polymer gel using different MRI sequencesNícollas Gonçalves Cavedini0https://orcid.org/0000-0002-9444-6534Ricardo Meurer Papaléo1https://orcid.org/0000-0003-3726-8951Nícolas Borges Jobim2https://orcid.org/0000-0001-5407-3318Phelipi Nunes Schuck3Fabrício Nery Garrafiel4https://orcid.org/0000-0002-8407-9160Elisa Magno Nunes de Oliveira5Marcelo Menna Barreto Schwarcke6https://orcid.org/0000-0002-1663-6754Alex Cristóvão Holanda de Oliveira7https://orcid.org/0000-0002-9240-3354Paulo Rauli Rafeson Vasconcelos Caribé8Ana Maria Marques da Silva9PUCRSPUCRSPUCRSWeill Cornell Medical CollegeHospital São Lucas da PUCRSPUCRSFederal University of Health Sciences of Porto AlegreFaculdade Nova EsperançaGhent UniversityPUCRSThis study aims to evaluate the dose sensitivity of MAGIC-f gel irradiated by high-energy photon beams, comparing quantification using different MRI sequences. Irradiation was performed using 6 MV photons with 600 cGy/min dose rate, field size of 20x20 cm², and 94 cm source-to-surface distance. Two gel batches were produced on different days and placed in vials. In the first batch, doses of 0, 2, 4, 6, 8, 10, 20, and 40 Gy were planned. The second batch was irradiated with doses of 0, 2, 4, 6, 10, 12, 14, and 16 Gy. MR images were acquired with Spin Echo (SE, TR=3 s) and Multi Spin Echo (MSE, TR = 3s or 10s, turbo factor 24) sequences. The dose is assessed via changes in the transverse relaxation time in the irradiated gel. In MSE, dose sensitivity in the first batch was 0.27 (TR=3 s) and 0.28 Gy-1s-1 (TR=10 s) and in the second batch, 0.31 and 0.31 Gy-1s-1 (TR = 3 s and TR = 10 s, respectively). In the SE sequence, dose sensitivity was 0.42 for the first batch and 0.43 Gy-1s-1 for the second batch. Linearity of dose-response was only obtained for doses below 10 Gy. Comparing the dose sensitivity extracted from MSE and SE sequences using TR= 3s, differences around 30% were found. Thus, although MSE-MRI offers a faster protocol of imaging acquisition it is less precise for quantification of relaxation times, as TE is not a well-defined quantity. The performance of the gel as a dosimeter is consequently sequence dependent.https://bjrs.org.br/revista/index.php/REVISTA/article/view/2085dosimetric gelmagic-f3d dosimetrymagnetic resonancespin echo |
| spellingShingle | Nícollas Gonçalves Cavedini Ricardo Meurer Papaléo Nícolas Borges Jobim Phelipi Nunes Schuck Fabrício Nery Garrafiel Elisa Magno Nunes de Oliveira Marcelo Menna Barreto Schwarcke Alex Cristóvão Holanda de Oliveira Paulo Rauli Rafeson Vasconcelos Caribé Ana Maria Marques da Silva Dose sensitivity of MAGIC-f polymer gel using different MRI sequences Brazilian Journal of Radiation Sciences dosimetric gel magic-f 3d dosimetry magnetic resonance spin echo |
| title | Dose sensitivity of MAGIC-f polymer gel using different MRI sequences |
| title_full | Dose sensitivity of MAGIC-f polymer gel using different MRI sequences |
| title_fullStr | Dose sensitivity of MAGIC-f polymer gel using different MRI sequences |
| title_full_unstemmed | Dose sensitivity of MAGIC-f polymer gel using different MRI sequences |
| title_short | Dose sensitivity of MAGIC-f polymer gel using different MRI sequences |
| title_sort | dose sensitivity of magic f polymer gel using different mri sequences |
| topic | dosimetric gel magic-f 3d dosimetry magnetic resonance spin echo |
| url | https://bjrs.org.br/revista/index.php/REVISTA/article/view/2085 |
| work_keys_str_mv | AT nicollasgoncalvescavedini dosesensitivityofmagicfpolymergelusingdifferentmrisequences AT ricardomeurerpapaleo dosesensitivityofmagicfpolymergelusingdifferentmrisequences AT nicolasborgesjobim dosesensitivityofmagicfpolymergelusingdifferentmrisequences AT phelipinunesschuck dosesensitivityofmagicfpolymergelusingdifferentmrisequences AT fabricionerygarrafiel dosesensitivityofmagicfpolymergelusingdifferentmrisequences AT elisamagnonunesdeoliveira dosesensitivityofmagicfpolymergelusingdifferentmrisequences AT marcelomennabarretoschwarcke dosesensitivityofmagicfpolymergelusingdifferentmrisequences AT alexcristovaoholandadeoliveira dosesensitivityofmagicfpolymergelusingdifferentmrisequences AT pauloraulirafesonvasconceloscaribe dosesensitivityofmagicfpolymergelusingdifferentmrisequences AT anamariamarquesdasilva dosesensitivityofmagicfpolymergelusingdifferentmrisequences |