Postextractive Alveolar Ridge Preservation Using L-PRF: Clinical and Histological Evaluation

Leukocyte- and platelet-rich fibrin (L-PRF) is an autologous platelet concentrate rich in growth factors and plasma proteins, obtained by centrifugation of patient whole blood, and widely used in oral surgery. This report describes a case of alveolar ridge preservation with L-PRF membranes. Postextr...

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Main Authors: Giorgio Serafini, Marco Lollobrigida, Lorenzo Fortunato, Giulia Mazzucchi, Luca Lamazza, Dario Di Nardo, Iole Vozza, Mara Riminucci, Alberto De Biase
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Dentistry
Online Access:http://dx.doi.org/10.1155/2020/5073519
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author Giorgio Serafini
Marco Lollobrigida
Lorenzo Fortunato
Giulia Mazzucchi
Luca Lamazza
Dario Di Nardo
Iole Vozza
Mara Riminucci
Alberto De Biase
author_facet Giorgio Serafini
Marco Lollobrigida
Lorenzo Fortunato
Giulia Mazzucchi
Luca Lamazza
Dario Di Nardo
Iole Vozza
Mara Riminucci
Alberto De Biase
author_sort Giorgio Serafini
collection DOAJ
description Leukocyte- and platelet-rich fibrin (L-PRF) is an autologous platelet concentrate rich in growth factors and plasma proteins, obtained by centrifugation of patient whole blood, and widely used in oral surgery. This report describes a case of alveolar ridge preservation with L-PRF membranes. Postextractive alveolar healing was then assessed through a histologic and histomorphometric analysis. A patient requiring tooth extraction and subsequent implant rehabilitation was treated with simple extraction and socket filling with L-PRF membranes. Implant placement was performed at 3 months, and a bone biopsy was obtained for histomorphometric analysis. Histological examination of the grafted sites showed that the use of L-PRF could achieve good results in terms of bone dimension and quality and soft tissue healing. The results of this study support the use of L-PRF membranes to preserve hard and soft tissues after tooth extraction.
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institution Kabale University
issn 2090-6447
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language English
publishDate 2020-01-01
publisher Wiley
record_format Article
series Case Reports in Dentistry
spelling doaj-art-cb24bb069e2e421b931f7b7d8a88693f2025-02-03T01:03:50ZengWileyCase Reports in Dentistry2090-64472090-64552020-01-01202010.1155/2020/50735195073519Postextractive Alveolar Ridge Preservation Using L-PRF: Clinical and Histological EvaluationGiorgio Serafini0Marco Lollobrigida1Lorenzo Fortunato2Giulia Mazzucchi3Luca Lamazza4Dario Di Nardo5Iole Vozza6Mara Riminucci7Alberto De Biase8Department of Oral and Maxillo Facial Sciences, “Sapienza” University of Rome, ItalyDepartment of Oral and Maxillo Facial Sciences, “Sapienza” University of Rome, ItalyDepartment of Oral and Maxillo Facial Sciences, “Sapienza” University of Rome, ItalyDepartment of Oral and Maxillo Facial Sciences, “Sapienza” University of Rome, ItalyDepartment of Oral and Maxillo Facial Sciences, “Sapienza” University of Rome, ItalyDepartment of Oral and Maxillo Facial Sciences, “Sapienza” University of Rome, ItalyDepartment of Oral and Maxillo Facial Sciences, “Sapienza” University of Rome, ItalyDepartment of Molecular Medicine, “Sapienza” University of Rome, ItalyDepartment of Oral and Maxillo Facial Sciences, “Sapienza” University of Rome, ItalyLeukocyte- and platelet-rich fibrin (L-PRF) is an autologous platelet concentrate rich in growth factors and plasma proteins, obtained by centrifugation of patient whole blood, and widely used in oral surgery. This report describes a case of alveolar ridge preservation with L-PRF membranes. Postextractive alveolar healing was then assessed through a histologic and histomorphometric analysis. A patient requiring tooth extraction and subsequent implant rehabilitation was treated with simple extraction and socket filling with L-PRF membranes. Implant placement was performed at 3 months, and a bone biopsy was obtained for histomorphometric analysis. Histological examination of the grafted sites showed that the use of L-PRF could achieve good results in terms of bone dimension and quality and soft tissue healing. The results of this study support the use of L-PRF membranes to preserve hard and soft tissues after tooth extraction.http://dx.doi.org/10.1155/2020/5073519
spellingShingle Giorgio Serafini
Marco Lollobrigida
Lorenzo Fortunato
Giulia Mazzucchi
Luca Lamazza
Dario Di Nardo
Iole Vozza
Mara Riminucci
Alberto De Biase
Postextractive Alveolar Ridge Preservation Using L-PRF: Clinical and Histological Evaluation
Case Reports in Dentistry
title Postextractive Alveolar Ridge Preservation Using L-PRF: Clinical and Histological Evaluation
title_full Postextractive Alveolar Ridge Preservation Using L-PRF: Clinical and Histological Evaluation
title_fullStr Postextractive Alveolar Ridge Preservation Using L-PRF: Clinical and Histological Evaluation
title_full_unstemmed Postextractive Alveolar Ridge Preservation Using L-PRF: Clinical and Histological Evaluation
title_short Postextractive Alveolar Ridge Preservation Using L-PRF: Clinical and Histological Evaluation
title_sort postextractive alveolar ridge preservation using l prf clinical and histological evaluation
url http://dx.doi.org/10.1155/2020/5073519
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