The impact of linked color imaging on adenoma detection rate in colonoscopy: a systematic review and meta-analysis

Background/Aims Colorectal cancer prevention relies on surveillance colonoscopy, with the adenoma detection rate as a key factor in examination quality. Linked color imaging (LCI) enhances lesion contrast and improves the examination performance. This systematic review and meta-analysis aimed to eva...

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Main Authors: Bruna Haueisen Figueiredo Zwetkoff, Luiz Ronaldo Alberti, Fábio Gontijo Rodrigues, Nelson Carvas Junior, José Celso Ardengh, Otavio Micelli Neto, Fernando Rodrigues Guzman, Marcelo Morganti Ferreira Dias, Guilherme Camarotti de Oliveira Canejo, Carlos Eduardo Oliveira dos Santos
Format: Article
Language:English
Published: Korean Society of Gastrointestinal Endoscopy 2025-03-01
Series:Clinical Endoscopy
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Online Access:http://e-ce.org/upload/pdf/ce-2024-072.pdf
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author Bruna Haueisen Figueiredo Zwetkoff
Luiz Ronaldo Alberti
Fábio Gontijo Rodrigues
Nelson Carvas Junior
José Celso Ardengh
Otavio Micelli Neto
Fernando Rodrigues Guzman
Marcelo Morganti Ferreira Dias
Guilherme Camarotti de Oliveira Canejo
Carlos Eduardo Oliveira dos Santos
author_facet Bruna Haueisen Figueiredo Zwetkoff
Luiz Ronaldo Alberti
Fábio Gontijo Rodrigues
Nelson Carvas Junior
José Celso Ardengh
Otavio Micelli Neto
Fernando Rodrigues Guzman
Marcelo Morganti Ferreira Dias
Guilherme Camarotti de Oliveira Canejo
Carlos Eduardo Oliveira dos Santos
author_sort Bruna Haueisen Figueiredo Zwetkoff
collection DOAJ
description Background/Aims Colorectal cancer prevention relies on surveillance colonoscopy, with the adenoma detection rate as a key factor in examination quality. Linked color imaging (LCI) enhances lesion contrast and improves the examination performance. This systematic review and meta-analysis aimed to evaluate the effect of LCI on adenoma detection rate in adults who underwent colonoscopy. Methods We searched the Medline, PubMed, BIREME, LILACS, and Scientific Electronic Library Online databases for randomized controlled trials comparing the use of LCI versus white light imaging (WLI), published up to March 2023. The outcomes included lesion characteristics, number of adenomas per patient, and the additional polyp detection rate. Results Sixteen studies were included in the analysis, which showed that LCI was more accurate than WLI in detecting adenomas, with an increased number of adenomas detected per patient. Although LCI performed well in terms of lesion size, morphology, and location, the subgroup analyses did not reveal any statistically significant differences between LCI and WLI. The addition of LCI did not result in significant improvements in the detection of serrated lesions, and there were no differences in the withdrawal time between groups. Conclusions LCI has been shown to be effective in detecting colonic lesions, improving the number of adenomas detected per patient and improving polyp detection rate without negatively affecting other quality criteria in colonoscopy.
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spelling doaj-art-cb21a1506ca34a56a36dbdf266e12e342025-08-20T03:05:45ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432025-03-0158222523910.5946/ce.2024.0727911The impact of linked color imaging on adenoma detection rate in colonoscopy: a systematic review and meta-analysisBruna Haueisen Figueiredo Zwetkoff0Luiz Ronaldo Alberti1Fábio Gontijo Rodrigues2Nelson Carvas Junior3José Celso Ardengh4Otavio Micelli Neto5Fernando Rodrigues Guzman6Marcelo Morganti Ferreira Dias7Guilherme Camarotti de Oliveira Canejo8Carlos Eduardo Oliveira dos Santos9 School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil School of Medicine, Federal University of Minas Gerais, Belo Horizonte, Brazil Federal University of Sao Paulo, Sao Paulo, Brazil Endoscopic Unit, Moriah Hospital, Sao Paulo, Brazil Endoscopic Unit, Moriah Hospital, Sao Paulo, Brazil Endoscopic Unit, Moriah Hospital, Sao Paulo, Brazil Endoscopic Unit, Moriah Hospital, Sao Paulo, Brazil Endoscopic Unit, Moriah Hospital, Sao Paulo, Brazil Santa Casa de Caridade de Bagé Hospital, Bagé, BrazilBackground/Aims Colorectal cancer prevention relies on surveillance colonoscopy, with the adenoma detection rate as a key factor in examination quality. Linked color imaging (LCI) enhances lesion contrast and improves the examination performance. This systematic review and meta-analysis aimed to evaluate the effect of LCI on adenoma detection rate in adults who underwent colonoscopy. Methods We searched the Medline, PubMed, BIREME, LILACS, and Scientific Electronic Library Online databases for randomized controlled trials comparing the use of LCI versus white light imaging (WLI), published up to March 2023. The outcomes included lesion characteristics, number of adenomas per patient, and the additional polyp detection rate. Results Sixteen studies were included in the analysis, which showed that LCI was more accurate than WLI in detecting adenomas, with an increased number of adenomas detected per patient. Although LCI performed well in terms of lesion size, morphology, and location, the subgroup analyses did not reveal any statistically significant differences between LCI and WLI. The addition of LCI did not result in significant improvements in the detection of serrated lesions, and there were no differences in the withdrawal time between groups. Conclusions LCI has been shown to be effective in detecting colonic lesions, improving the number of adenomas detected per patient and improving polyp detection rate without negatively affecting other quality criteria in colonoscopy.http://e-ce.org/upload/pdf/ce-2024-072.pdfadenomacolonoscopycolorectal neoplasmsdiagnostic techniques and procedures
spellingShingle Bruna Haueisen Figueiredo Zwetkoff
Luiz Ronaldo Alberti
Fábio Gontijo Rodrigues
Nelson Carvas Junior
José Celso Ardengh
Otavio Micelli Neto
Fernando Rodrigues Guzman
Marcelo Morganti Ferreira Dias
Guilherme Camarotti de Oliveira Canejo
Carlos Eduardo Oliveira dos Santos
The impact of linked color imaging on adenoma detection rate in colonoscopy: a systematic review and meta-analysis
Clinical Endoscopy
adenoma
colonoscopy
colorectal neoplasms
diagnostic techniques and procedures
title The impact of linked color imaging on adenoma detection rate in colonoscopy: a systematic review and meta-analysis
title_full The impact of linked color imaging on adenoma detection rate in colonoscopy: a systematic review and meta-analysis
title_fullStr The impact of linked color imaging on adenoma detection rate in colonoscopy: a systematic review and meta-analysis
title_full_unstemmed The impact of linked color imaging on adenoma detection rate in colonoscopy: a systematic review and meta-analysis
title_short The impact of linked color imaging on adenoma detection rate in colonoscopy: a systematic review and meta-analysis
title_sort impact of linked color imaging on adenoma detection rate in colonoscopy a systematic review and meta analysis
topic adenoma
colonoscopy
colorectal neoplasms
diagnostic techniques and procedures
url http://e-ce.org/upload/pdf/ce-2024-072.pdf
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