Computational frameworks transform antagonism to synergy in optimizing combination therapies
Abstract While drug combinations are increasingly important in disease treatment, predicting their therapeutic interactions remains challenging. This review systematically analyzes computational methods for predicting drug combination effects through multi-omics data integration. We comprehensively...
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Main Authors: | Jinghong Chen, Anqi Lin, Aimin Jiang, Chang Qi, Zaoqu Liu, Quan Cheng, Shuofeng Yuan, Peng Luo |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2025-01-01
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Series: | npj Digital Medicine |
Online Access: | https://doi.org/10.1038/s41746-025-01435-2 |
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