Pre-infarction angina and ischemic pre-conditioning role in coronary reserve protection during early post-infarction period
Aim. To study coronary reserve features, in regard to angina attacks prior to myocardial infarction (MI) and ischemic pre-conditioning (IPC) phenomenon. Materials and methods. In total, among 78 patients with Q-wave MI, previously diagnosed coronary heart disease (CHD) preceded MI in 61.5% of cases....
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
2006-02-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/1115 |
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| author | A. P. Ivanov T. S. Gornostaeva I. A. Elgardt |
| author_facet | A. P. Ivanov T. S. Gornostaeva I. A. Elgardt |
| author_sort | A. P. Ivanov |
| collection | DOAJ |
| description | Aim. To study coronary reserve features, in regard to angina attacks prior to myocardial infarction (MI) and ischemic pre-conditioning (IPC) phenomenon. Materials and methods. In total, among 78 patients with Q-wave MI, previously diagnosed coronary heart disease (CHD) preceded MI in 61.5% of cases. IPC was diagnosed in 59% of the participants, by repeated stress tests and Holter electrocardiogram monitoring (ECG HM). Results. Both mechanisms of ischemic myocardial protection were associated with better tolerance to physical stress, but had some differences in myocardial ischemia severity. In IPC, myocardial ischemia was characterized by substantial increase in painless ischemic episode rates, with circadian variation in ischemic threshold. Vasospasm might play a role in IPC phenomenon development among MI patients. Therefore, complex study of coronary reserve in such patients, by stress testing with parallel ECG HM, is necessary. Conclusion. IPC and pre-MI angina have protective effects in MI patients. Vasospastic component plays a role in IPC development. |
| format | Article |
| id | doaj-art-cb1bf265180e44cf821a99a0b115ac49 |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2006-02-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-cb1bf265180e44cf821a99a0b115ac492025-08-20T03:43:27Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252006-02-01517175827Pre-infarction angina and ischemic pre-conditioning role in coronary reserve protection during early post-infarction periodA. P. Ivanov0T. S. Gornostaeva1I. A. Elgardt2Tver Medical Academy, Tver Cardiology Dispanser. TverTver Medical Academy, Tver Cardiology Dispanser. TverTver Medical Academy, Tver Cardiology Dispanser. TverAim. To study coronary reserve features, in regard to angina attacks prior to myocardial infarction (MI) and ischemic pre-conditioning (IPC) phenomenon. Materials and methods. In total, among 78 patients with Q-wave MI, previously diagnosed coronary heart disease (CHD) preceded MI in 61.5% of cases. IPC was diagnosed in 59% of the participants, by repeated stress tests and Holter electrocardiogram monitoring (ECG HM). Results. Both mechanisms of ischemic myocardial protection were associated with better tolerance to physical stress, but had some differences in myocardial ischemia severity. In IPC, myocardial ischemia was characterized by substantial increase in painless ischemic episode rates, with circadian variation in ischemic threshold. Vasospasm might play a role in IPC phenomenon development among MI patients. Therefore, complex study of coronary reserve in such patients, by stress testing with parallel ECG HM, is necessary. Conclusion. IPC and pre-MI angina have protective effects in MI patients. Vasospastic component plays a role in IPC development.https://cardiovascular.elpub.ru/jour/article/view/1115ischemic preconditioningangina prior to myocardial infarctionischemic adaptation |
| spellingShingle | A. P. Ivanov T. S. Gornostaeva I. A. Elgardt Pre-infarction angina and ischemic pre-conditioning role in coronary reserve protection during early post-infarction period Кардиоваскулярная терапия и профилактика ischemic preconditioning angina prior to myocardial infarction ischemic adaptation |
| title | Pre-infarction angina and ischemic pre-conditioning role in coronary reserve protection during early post-infarction period |
| title_full | Pre-infarction angina and ischemic pre-conditioning role in coronary reserve protection during early post-infarction period |
| title_fullStr | Pre-infarction angina and ischemic pre-conditioning role in coronary reserve protection during early post-infarction period |
| title_full_unstemmed | Pre-infarction angina and ischemic pre-conditioning role in coronary reserve protection during early post-infarction period |
| title_short | Pre-infarction angina and ischemic pre-conditioning role in coronary reserve protection during early post-infarction period |
| title_sort | pre infarction angina and ischemic pre conditioning role in coronary reserve protection during early post infarction period |
| topic | ischemic preconditioning angina prior to myocardial infarction ischemic adaptation |
| url | https://cardiovascular.elpub.ru/jour/article/view/1115 |
| work_keys_str_mv | AT apivanov preinfarctionanginaandischemicpreconditioningroleincoronaryreserveprotectionduringearlypostinfarctionperiod AT tsgornostaeva preinfarctionanginaandischemicpreconditioningroleincoronaryreserveprotectionduringearlypostinfarctionperiod AT iaelgardt preinfarctionanginaandischemicpreconditioningroleincoronaryreserveprotectionduringearlypostinfarctionperiod |