Salvage treatment strategies for refractory sudden sensorineural hearing loss—a comprehensive review and meta-analysis with practical recommendations

Salvage treatment strategies for refractory sudden sensorineural hearing loss—a comprehensive review and meta-analysis with practical recommendations

BackgroundSudden sensorineural hearing loss (SSNHL) affects up to 27 per 100,000 people annually, with more than half not regaining full hearing after following standard therapy. Identifying effective salvage treatments for refractory cases is critical to improve outcomes and reduce long-term audito...

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Bibliographic Details
Main Authors: Piero Giuseppe Meliante, Luigi D’Avino, Giuseppe Barba, Edoardo Covelli, Carla Petrella, Christian Barbato, Antonio Minni
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Neurology
Subjects:
hearing loss
sudden
glucocorticoids/therapeutic use
intratympanic injection
hyperbaric oxygenation (HBO)
treatment outcome
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2025.1627892/full
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