Oral manifestations of thrombocytopaenia
The appearance in the mouth of haemorrhagic petechiae, ecchymoses or blood blisters with spontaneous bleeding is suggestive of a haemorrhagic disorder that may be caused either by functional impairment of platelets or of blood vessel walls, by an abnormal decrease in the number of circulating platel...
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| Format: | Article |
| Language: | English |
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Springer
2018-01-01
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| Series: | Saudi Dental Journal |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1013905217300627 |
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| author | R.A.G. Khammissa J. Fourie A. Masilana S. Lawrence J. Lemmer L. Feller |
| author_facet | R.A.G. Khammissa J. Fourie A. Masilana S. Lawrence J. Lemmer L. Feller |
| author_sort | R.A.G. Khammissa |
| collection | DOAJ |
| description | The appearance in the mouth of haemorrhagic petechiae, ecchymoses or blood blisters with spontaneous bleeding is suggestive of a haemorrhagic disorder that may be caused either by functional impairment of platelets or of blood vessel walls, by an abnormal decrease in the number of circulating platelets (thrombocytopaenia), or by defects in the blood clotting mechanism. Thrombocytopaenia from decreased production or increased destruction of platelets may be caused by multiple factors including immune mediated mechanisms, drugs or infections.A diagnosis of thrombocytopaenic purpura can be made when any other disease entity that might be causing the purpura is excluded on the basis of the medical history, the physical examination, a complete blood count and a peripheral blood smear.In this paper, we outline the clinical features of oral thrombocytopaenic purpura and briefly discuss some aspects of its aetiopathogenesis and treatment. Keywords: Ecchymosis, Petechiae, Haemorrhagic blister, Immune mediated thrombocytopaenia |
| format | Article |
| id | doaj-art-cb1675c54ce449deb3e324663cb6f6db |
| institution | DOAJ |
| issn | 1013-9052 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Springer |
| record_format | Article |
| series | Saudi Dental Journal |
| spelling | doaj-art-cb1675c54ce449deb3e324663cb6f6db2025-08-20T03:23:38ZengSpringerSaudi Dental Journal1013-90522018-01-01301192510.1016/j.sdentj.2017.08.004Oral manifestations of thrombocytopaeniaR.A.G. Khammissa0J. Fourie1A. Masilana2S. Lawrence3J. Lemmer4L. Feller5Department of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria, South AfricaDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria, South AfricaDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria, South AfricaDepartment of Periodontology and Oral Medicine, University of the Western Cape, Cape Town, South AfricaDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria, South AfricaDepartment of Periodontology and Oral Medicine, Sefako Makgatho Health Sciences University, Pretoria, South Africa; Corresponding author at: Dept. Periodontology and Oral Medicine, Box D26 School of Dentistry, Sefako Makgatho Health Sciences University, Medunsa 0204, South Africa.The appearance in the mouth of haemorrhagic petechiae, ecchymoses or blood blisters with spontaneous bleeding is suggestive of a haemorrhagic disorder that may be caused either by functional impairment of platelets or of blood vessel walls, by an abnormal decrease in the number of circulating platelets (thrombocytopaenia), or by defects in the blood clotting mechanism. Thrombocytopaenia from decreased production or increased destruction of platelets may be caused by multiple factors including immune mediated mechanisms, drugs or infections.A diagnosis of thrombocytopaenic purpura can be made when any other disease entity that might be causing the purpura is excluded on the basis of the medical history, the physical examination, a complete blood count and a peripheral blood smear.In this paper, we outline the clinical features of oral thrombocytopaenic purpura and briefly discuss some aspects of its aetiopathogenesis and treatment. Keywords: Ecchymosis, Petechiae, Haemorrhagic blister, Immune mediated thrombocytopaeniahttp://www.sciencedirect.com/science/article/pii/S1013905217300627 |
| spellingShingle | R.A.G. Khammissa J. Fourie A. Masilana S. Lawrence J. Lemmer L. Feller Oral manifestations of thrombocytopaenia Saudi Dental Journal |
| title | Oral manifestations of thrombocytopaenia |
| title_full | Oral manifestations of thrombocytopaenia |
| title_fullStr | Oral manifestations of thrombocytopaenia |
| title_full_unstemmed | Oral manifestations of thrombocytopaenia |
| title_short | Oral manifestations of thrombocytopaenia |
| title_sort | oral manifestations of thrombocytopaenia |
| url | http://www.sciencedirect.com/science/article/pii/S1013905217300627 |
| work_keys_str_mv | AT ragkhammissa oralmanifestationsofthrombocytopaenia AT jfourie oralmanifestationsofthrombocytopaenia AT amasilana oralmanifestationsofthrombocytopaenia AT slawrence oralmanifestationsofthrombocytopaenia AT jlemmer oralmanifestationsofthrombocytopaenia AT lfeller oralmanifestationsofthrombocytopaenia |