Comparison of in vitro anti-Staphylococcus aureus activity of eight antibiotics and four dilutions of propolis

The objective of this research was based on the comparison of inhibition halos of a sample of Staphylococcus aureus, faced in vitro with eight antibiotics used in medicine, as well as four alcoholic concentrations of propolis. The results indicate that the antimicrobial action of propolis, depending...

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Main Authors: Ken Jact Fernández-León, José Antonio Rodríguez-Díaz, Lisandra Reyes-Espinosa, Amílcar Duquesne-Alderete, Yovanni Orestes Solenzal-Valdivia, Alayn Rives-Quintero, Juan Emilio Hernández-García
Format: Article
Language:Spanish
Published: Selva Andina Research Society 2022-02-01
Series:Journal of the Selva Andina Research Society
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Online Access:http://www.scielo.org.bo/scielo.php?script=sci_arttext&pid=S2072-92942022000100035&lng=es&nrm=iso&tlng=en
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author Ken Jact Fernández-León
José Antonio Rodríguez-Díaz
Lisandra Reyes-Espinosa
Amílcar Duquesne-Alderete
Yovanni Orestes Solenzal-Valdivia
Alayn Rives-Quintero
Juan Emilio Hernández-García
author_facet Ken Jact Fernández-León
José Antonio Rodríguez-Díaz
Lisandra Reyes-Espinosa
Amílcar Duquesne-Alderete
Yovanni Orestes Solenzal-Valdivia
Alayn Rives-Quintero
Juan Emilio Hernández-García
author_sort Ken Jact Fernández-León
collection DOAJ
description The objective of this research was based on the comparison of inhibition halos of a sample of Staphylococcus aureus, faced in vitro with eight antibiotics used in medicine, as well as four alcoholic concentrations of propolis. The results indicate that the antimicrobial action of propolis, depending on the bioactive compounds such as: flavonoids, polyphenols, aromatic acids, etc., contained in this product. The antibacterial activity of the four propolis dilutions produced inhibition halos between 10 and 20 mm. Of the eight antibiotics with which the comparison was made, only erythromycin was found to be resistant to S. aureus. Penicillin produced halos with smaller dimensions. Although the halos derived from the rest of the antimicrobials were greater than those from propolis, many of them were found within the range originated by said product from the hive. Compared antibacterial resistance has not been demonstrated, with which over the year’s antibiotics present, when used indiscriminately to eliminate or control antimicrobial agents
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institution DOAJ
issn 2072-9294
2072-9308
language Spanish
publishDate 2022-02-01
publisher Selva Andina Research Society
record_format Article
series Journal of the Selva Andina Research Society
spelling doaj-art-cb06d54d2c1b4b738596ba5e4ee530aa2025-08-20T03:03:53ZspaSelva Andina Research SocietyJournal of the Selva Andina Research Society2072-92942072-93082022-02-011313548doi:10.36610/j.jsars.2022.130100035Comparison of in vitro anti-Staphylococcus aureus activity of eight antibiotics and four dilutions of propolisKen Jact Fernández-León0https://orcid.org/0000-0001-7475-0638José Antonio Rodríguez-Díaz1https://orcid.org/0000-0002-7451-5627Lisandra Reyes-Espinosa2https://orcid.org/0000-0002-8894-342XAmílcar Duquesne-Alderete3https://orcid.org/0000-0003-3928-3987Yovanni Orestes Solenzal-Valdivia4https://orcid.org/0000-0002-6188-7237Alayn Rives-Quintero5https://orcid.org/0000-0002-6377-1473Juan Emilio Hernández-García6https://orcid.org/0000-0002-7471-0561Development of the Ministry of Agriculture of Cuba. Reference Laboratory for Apicultural Research and Health (LARISA). Address: Esquina Carretera Circunvalante S/N, Sancti Spirítus. Cuba. Tel: 41375652-52992653. Development of the Ministry of Agriculture of Cuba. Reference Laboratory for Apicultural Research and Health (LARISA). Address: Esquina Carretera Circunvalante S/N, Sancti Spirítus. Cuba. Tel: 41375652-52992653. Center for Molecular Immunology. Calle 216 esq. A 15, Atabey, Playa. Habana. Cuba. Tel: 76384460-53189615.Fructuoso Rodriguez Orthopedic Teaching Hospital. Address: F Street corner 29. Vedado. Revolution Square. Habana. Cuba. Tel: 53249870-78836655.Development of the Ministry of Agriculture of Cuba. Reference Laboratory for Apicultural Research and Health (LARISA). Address: Esquina Carretera Circunvalante S/N, Sancti Spirítus. Cuba. Tel: 41375652-52992653Development of the Ministry of Agriculture of Cuba. Reference Laboratory for Apicultural Research and Health (LARISA). Address: Esquina Carretera Circunvalante S/N, Sancti Spirítus. Cuba. Tel: 41375652-52992653University of Sancti Spíritus "José Martí Pérez". Faculty of Agricultural Sciences. Cuba. Carretera Central, Esquina Paseo S/NThe objective of this research was based on the comparison of inhibition halos of a sample of Staphylococcus aureus, faced in vitro with eight antibiotics used in medicine, as well as four alcoholic concentrations of propolis. The results indicate that the antimicrobial action of propolis, depending on the bioactive compounds such as: flavonoids, polyphenols, aromatic acids, etc., contained in this product. The antibacterial activity of the four propolis dilutions produced inhibition halos between 10 and 20 mm. Of the eight antibiotics with which the comparison was made, only erythromycin was found to be resistant to S. aureus. Penicillin produced halos with smaller dimensions. Although the halos derived from the rest of the antimicrobials were greater than those from propolis, many of them were found within the range originated by said product from the hive. Compared antibacterial resistance has not been demonstrated, with which over the year’s antibiotics present, when used indiscriminately to eliminate or control antimicrobial agentshttp://www.scielo.org.bo/scielo.php?script=sci_arttext&pid=S2072-92942022000100035&lng=es&nrm=iso&tlng=enpropolis; ethanolic extract; antimicrobial; halos; inhibition
spellingShingle Ken Jact Fernández-León
José Antonio Rodríguez-Díaz
Lisandra Reyes-Espinosa
Amílcar Duquesne-Alderete
Yovanni Orestes Solenzal-Valdivia
Alayn Rives-Quintero
Juan Emilio Hernández-García
Comparison of in vitro anti-Staphylococcus aureus activity of eight antibiotics and four dilutions of propolis
Journal of the Selva Andina Research Society
propolis; ethanolic extract; antimicrobial; halos; inhibition
title Comparison of in vitro anti-Staphylococcus aureus activity of eight antibiotics and four dilutions of propolis
title_full Comparison of in vitro anti-Staphylococcus aureus activity of eight antibiotics and four dilutions of propolis
title_fullStr Comparison of in vitro anti-Staphylococcus aureus activity of eight antibiotics and four dilutions of propolis
title_full_unstemmed Comparison of in vitro anti-Staphylococcus aureus activity of eight antibiotics and four dilutions of propolis
title_short Comparison of in vitro anti-Staphylococcus aureus activity of eight antibiotics and four dilutions of propolis
title_sort comparison of in vitro anti staphylococcus aureus activity of eight antibiotics and four dilutions of propolis
topic propolis; ethanolic extract; antimicrobial; halos; inhibition
url http://www.scielo.org.bo/scielo.php?script=sci_arttext&pid=S2072-92942022000100035&lng=es&nrm=iso&tlng=en
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