A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitis
Purpose: to demonstrate a case of hemolytic-uremic syndrome (HUS) in a 5-year-old child associated with an acute intestinal infection of unknown etiology, occurring with hemocolitis. Results. During clinical and laboratory observation, edematous syndrome, oligoanuria, severe microangiopathic hemolyt...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
LLC "Diagnostics and Vaccines"
2024-03-01
|
| Series: | Детские инфекции (Москва) |
| Subjects: | |
| Online Access: | https://detinf.elpub.ru/jour/article/view/920 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850074504486715392 |
|---|---|
| author | O. V. Molochkova S. B. Orekhova R. V. Ovechkin V. S. Vyshlova V. V. Glukhova O. B. Kovalev N. Yu. Egorova A. B. Chashchukhina V. A. Masyakin E. P. Egorova A. A. Sakharova A. G. Okhtyarkina |
| author_facet | O. V. Molochkova S. B. Orekhova R. V. Ovechkin V. S. Vyshlova V. V. Glukhova O. B. Kovalev N. Yu. Egorova A. B. Chashchukhina V. A. Masyakin E. P. Egorova A. A. Sakharova A. G. Okhtyarkina |
| author_sort | O. V. Molochkova |
| collection | DOAJ |
| description | Purpose: to demonstrate a case of hemolytic-uremic syndrome (HUS) in a 5-year-old child associated with an acute intestinal infection of unknown etiology, occurring with hemocolitis. Results. During clinical and laboratory observation, edematous syndrome, oligoanuria, severe microangiopathic hemolytic anemia (decrease in hemoglobin, haptoglobin, increase in Lactate dehydrogenase), thrombocytopenia, consumption coagulopathy, hyperazotemia, acute kidney injury (AKI) according to KDIGO grade 2 (increase in serum creatinine more than 2 times) developed. As part of complex therapy with balanced crystalloid solutions with stimulation of diuresis, it was possible to achieve rapid restoration of diuresis on the 2nd day of hospital stay without the use of renal replacement therapy; he also received antibiotics, anticoagulants, transfusion of fresh frozen plasma and red blood cell suspension. Hyperazotemia was relieved within 5 days, as was thrombocytopenia. The follow-up recovery of renal function showed. |
| format | Article |
| id | doaj-art-cb00c2c8a064446eb1294e46f0d8412e |
| institution | DOAJ |
| issn | 2072-8107 |
| language | Russian |
| publishDate | 2024-03-01 |
| publisher | LLC "Diagnostics and Vaccines" |
| record_format | Article |
| series | Детские инфекции (Москва) |
| spelling | doaj-art-cb00c2c8a064446eb1294e46f0d8412e2025-08-20T02:46:33ZrusLLC "Diagnostics and Vaccines"Детские инфекции (Москва)2072-81072024-03-01231626710.22627/2072-8107-2024-23-1-62-67656A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitisO. V. Molochkova0S. B. Orekhova1R. V. Ovechkin2V. S. Vyshlova3V. V. Glukhova4O. B. Kovalev5N. Yu. Egorova6A. B. Chashchukhina7V. A. Masyakin8E. P. Egorova9A. A. Sakharova10A. G. Okhtyarkina11Pirogov Russian National Research Medical UniversityChildren's City Clinical Hospital No. 9 named after. G.N. SperanskyPirogov Russian National Research Medical UniversityPirogov Russian National Research Medical UniversityPirogov Russian National Research Medical UniversityPirogov Russian National Research Medical UniversityPirogov Russian National Research Medical UniversityChildren's City Clinical Hospital No. 9 named after. G.N. SperanskyChildren's City Clinical Hospital No. 9 named after. G.N. SperanskyChildren's City Clinical Hospital No. 9 named after. G.N. SperanskyChildren's City Clinical Hospital No. 9 named after. G.N. SperanskyMasyakin V. A.Pirogov Russian National Research Medical UniversityPurpose: to demonstrate a case of hemolytic-uremic syndrome (HUS) in a 5-year-old child associated with an acute intestinal infection of unknown etiology, occurring with hemocolitis. Results. During clinical and laboratory observation, edematous syndrome, oligoanuria, severe microangiopathic hemolytic anemia (decrease in hemoglobin, haptoglobin, increase in Lactate dehydrogenase), thrombocytopenia, consumption coagulopathy, hyperazotemia, acute kidney injury (AKI) according to KDIGO grade 2 (increase in serum creatinine more than 2 times) developed. As part of complex therapy with balanced crystalloid solutions with stimulation of diuresis, it was possible to achieve rapid restoration of diuresis on the 2nd day of hospital stay without the use of renal replacement therapy; he also received antibiotics, anticoagulants, transfusion of fresh frozen plasma and red blood cell suspension. Hyperazotemia was relieved within 5 days, as was thrombocytopenia. The follow-up recovery of renal function showed.https://detinf.elpub.ru/jour/article/view/920hemolytic-uremic syndromehusthrombotic microangiopathyтmaacute kidney injuryakichildrenacute intestinal infectionhemocolitis |
| spellingShingle | O. V. Molochkova S. B. Orekhova R. V. Ovechkin V. S. Vyshlova V. V. Glukhova O. B. Kovalev N. Yu. Egorova A. B. Chashchukhina V. A. Masyakin E. P. Egorova A. A. Sakharova A. G. Okhtyarkina A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitis Детские инфекции (Москва) hemolytic-uremic syndrome hus thrombotic microangiopathy тma acute kidney injury aki children acute intestinal infection hemocolitis |
| title | A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitis |
| title_full | A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitis |
| title_fullStr | A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitis |
| title_full_unstemmed | A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitis |
| title_short | A case of hemolytic-uremic syndrome that developed in a 5-year-old child due to acute intestinal infection with hemocolitis |
| title_sort | case of hemolytic uremic syndrome that developed in a 5 year old child due to acute intestinal infection with hemocolitis |
| topic | hemolytic-uremic syndrome hus thrombotic microangiopathy тma acute kidney injury aki children acute intestinal infection hemocolitis |
| url | https://detinf.elpub.ru/jour/article/view/920 |
| work_keys_str_mv | AT ovmolochkova acaseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT sborekhova acaseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT rvovechkin acaseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT vsvyshlova acaseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT vvglukhova acaseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT obkovalev acaseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT nyuegorova acaseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT abchashchukhina acaseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT vamasyakin acaseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT epegorova acaseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT aasakharova acaseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT agokhtyarkina acaseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT ovmolochkova caseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT sborekhova caseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT rvovechkin caseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT vsvyshlova caseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT vvglukhova caseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT obkovalev caseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT nyuegorova caseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT abchashchukhina caseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT vamasyakin caseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT epegorova caseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT aasakharova caseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis AT agokhtyarkina caseofhemolyticuremicsyndromethatdevelopedina5yearoldchildduetoacuteintestinalinfectionwithhemocolitis |