Design, Synthesis, and In Vitro and In Silico Biological Exploration of Novel Pyridine-Embedded 1,3,4-Oxadiazole Hybrids as Potential Antimicrobial Agents

Design, Synthesis, and In Vitro and In Silico Biological Exploration of Novel Pyridine-Embedded 1,3,4-Oxadiazole Hybrids as Potential Antimicrobial Agents

Antibiotic resistance represents a significant public health challenge in the current century. The β-lactam antibiotics, together with carbapenems, are inactivated by zinc-dependent bacterial enzymes called metallo-β-lactamases (MBLs). Presently there are no clinically permitted MBL inhibitors, and...

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Bibliographic Details
Main Authors:	Shivakumara K. N., Basavarajaiah S. M., Nagesh G. Y., Prashantha K., Yogesh M., Abhishek N. R., Odesha H. N.
Format:	Article
Language:	English
Published:	Wiley 2025-01-01
Series:	Journal of Chemistry
Online Access:	http://dx.doi.org/10.1155/joch/4427650
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