Phenotypic Characteristics and the Susceptibility of Haemophilus influenzae to the Antimicrobial Agents in Russia (2004 - 2016)
The aim. The study of phenotypic characteristics and dynamics of sensitivity to antibiotics Russian invasive strains H. influenzae. Materials and methods. Studied 89 Russian invasive strains H. influenzae for the period 13-year period (2004 - 2016). To study metabolic, enzymatic activity and beta-la...
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| Format: | Article |
| Language: | Russian |
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Numikom LLC
2017-04-01
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| Series: | Эпидемиология и вакцинопрофилактика |
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| Online Access: | https://www.epidemvac.ru/jour/article/view/253 |
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| author | M. A. Koroleva I. S. Koroleva I. M. Gruber L. S. Cherkasova |
| author_facet | M. A. Koroleva I. S. Koroleva I. M. Gruber L. S. Cherkasova |
| author_sort | M. A. Koroleva |
| collection | DOAJ |
| description | The aim. The study of phenotypic characteristics and dynamics of sensitivity to antibiotics Russian invasive strains H. influenzae. Materials and methods. Studied 89 Russian invasive strains H. influenzae for the period 13-year period (2004 - 2016). To study metabolic, enzymatic activity and beta-lactamase and biotype characteristics H. influenzae strains. Studied H. influenzae sensitivity to antibiotics. Results. Most strains related H. influenzae serotype b (86,1%), biotype II (69,7%), VII (16,9%), I (13,5%). Ampicillin-resistant strains accounted for 10.1%. All of them produced the enzyme beta-lactamase. Conclusion. The population of the Russian invasive ampicillin-resistant H. influenzae strains accounted for 10.1%. The mechanism of resistance to ampicillin is the production of the enzyme beta-lactamase. |
| format | Article |
| id | doaj-art-caf29e8300a946a58985fe4bf290e026 |
| institution | DOAJ |
| issn | 2073-3046 2619-0494 |
| language | Russian |
| publishDate | 2017-04-01 |
| publisher | Numikom LLC |
| record_format | Article |
| series | Эпидемиология и вакцинопрофилактика |
| spelling | doaj-art-caf29e8300a946a58985fe4bf290e0262025-08-20T03:00:50ZrusNumikom LLCЭпидемиология и вакцинопрофилактика2073-30462619-04942017-04-01162364310.31631/2073-3046-2017-16-2-36-43252Phenotypic Characteristics and the Susceptibility of Haemophilus influenzae to the Antimicrobial Agents in Russia (2004 - 2016)M. A. Koroleva0I. S. Koroleva1I. M. Gruber2L. S. Cherkasova3Federal Budget Institution of Science «Central Research Institute of Epidemiology» of The Federal Service on Customers Rights Protection and Human Well-being SurveillanceFederal Budget Institution of Science «Central Research Institute of Epidemiology» of The Federal Service on Customers Rights Protection and Human Well-being SurveillanceFederal State Budget Institution of Science «Research Institute of Vaccines and Sera», Russian Academy of Medical SciencesFederal State Budget Institution of Science «Research Institute of Vaccines and Sera», Russian Academy of Medical SciencesThe aim. The study of phenotypic characteristics and dynamics of sensitivity to antibiotics Russian invasive strains H. influenzae. Materials and methods. Studied 89 Russian invasive strains H. influenzae for the period 13-year period (2004 - 2016). To study metabolic, enzymatic activity and beta-lactamase and biotype characteristics H. influenzae strains. Studied H. influenzae sensitivity to antibiotics. Results. Most strains related H. influenzae serotype b (86,1%), biotype II (69,7%), VII (16,9%), I (13,5%). Ampicillin-resistant strains accounted for 10.1%. All of them produced the enzyme beta-lactamase. Conclusion. The population of the Russian invasive ampicillin-resistant H. influenzae strains accounted for 10.1%. The mechanism of resistance to ampicillin is the production of the enzyme beta-lactamase.https://www.epidemvac.ru/jour/article/view/253гемофильная инфекциягемофильная палочкаменингитрезистентность к антибактериальным препаратамhaemophilus influenzaemeningitisantimicrobial resistance |
| spellingShingle | M. A. Koroleva I. S. Koroleva I. M. Gruber L. S. Cherkasova Phenotypic Characteristics and the Susceptibility of Haemophilus influenzae to the Antimicrobial Agents in Russia (2004 - 2016) Эпидемиология и вакцинопрофилактика гемофильная инфекция гемофильная палочка менингит резистентность к антибактериальным препаратам haemophilus influenzae meningitis antimicrobial resistance |
| title | Phenotypic Characteristics and the Susceptibility of Haemophilus influenzae to the Antimicrobial Agents in Russia (2004 - 2016) |
| title_full | Phenotypic Characteristics and the Susceptibility of Haemophilus influenzae to the Antimicrobial Agents in Russia (2004 - 2016) |
| title_fullStr | Phenotypic Characteristics and the Susceptibility of Haemophilus influenzae to the Antimicrobial Agents in Russia (2004 - 2016) |
| title_full_unstemmed | Phenotypic Characteristics and the Susceptibility of Haemophilus influenzae to the Antimicrobial Agents in Russia (2004 - 2016) |
| title_short | Phenotypic Characteristics and the Susceptibility of Haemophilus influenzae to the Antimicrobial Agents in Russia (2004 - 2016) |
| title_sort | phenotypic characteristics and the susceptibility of haemophilus influenzae to the antimicrobial agents in russia 2004 2016 |
| topic | гемофильная инфекция гемофильная палочка менингит резистентность к антибактериальным препаратам haemophilus influenzae meningitis antimicrobial resistance |
| url | https://www.epidemvac.ru/jour/article/view/253 |
| work_keys_str_mv | AT makoroleva phenotypiccharacteristicsandthesusceptibilityofhaemophilusinfluenzaetotheantimicrobialagentsinrussia20042016 AT iskoroleva phenotypiccharacteristicsandthesusceptibilityofhaemophilusinfluenzaetotheantimicrobialagentsinrussia20042016 AT imgruber phenotypiccharacteristicsandthesusceptibilityofhaemophilusinfluenzaetotheantimicrobialagentsinrussia20042016 AT lscherkasova phenotypiccharacteristicsandthesusceptibilityofhaemophilusinfluenzaetotheantimicrobialagentsinrussia20042016 |