Development of Alzheimer’s disease in Down syndrome

Down syndrome (DS), caused by trisomy 21, is strongly associated with an increased risk of early-onset Alzheimer’s disease (AD). This work explores the cellular, genetic, epigenetic, and neuropsychological mechanisms that underlie the accelerated development of AD in individuals with DS. We review k...

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Bibliographic Details
Main Authors: Octavio García, Eduardo Domínguez-de-la-Cruz, Itzel Guadalupe Luna-Martínez, José Alfonso Garnett-Carbajal, Jesús Antonio Villegas-Piña
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2025-08-01
Series:Exploration of Neuroscience
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Online Access:https://www.explorationpub.com/uploads/Article/A1006104/1006104.pdf
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