Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological Evidence

Typical cat-scratch disease (CSD) is characterized by local lymphadenopathy following the scratch or bite from a cat or kitten. An atypical presentation which includes liver and/or spleen lesions is rarely reported in an immunocompetent child. Systemic CSD may mimic more serious disorders like malig...

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Main Authors: Serkan Atıcı, Eda Kepenekli Kadayıfcı, Ayşe Karaaslan, Muhammed Hasan Toper, Cigdem Ataizi Celikel, Ahmet Soysal, Mustafa Bakır
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2014/397437
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author Serkan Atıcı
Eda Kepenekli Kadayıfcı
Ayşe Karaaslan
Muhammed Hasan Toper
Cigdem Ataizi Celikel
Ahmet Soysal
Mustafa Bakır
author_facet Serkan Atıcı
Eda Kepenekli Kadayıfcı
Ayşe Karaaslan
Muhammed Hasan Toper
Cigdem Ataizi Celikel
Ahmet Soysal
Mustafa Bakır
author_sort Serkan Atıcı
collection DOAJ
description Typical cat-scratch disease (CSD) is characterized by local lymphadenopathy following the scratch or bite from a cat or kitten. An atypical presentation which includes liver and/or spleen lesions is rarely reported in an immunocompetent child. Systemic CSD may mimic more serious disorders like malignancy or tuberculosis. Although a diagnosis is difficult to establish in systemic CSD, an early diagnosis and an appropriate treatment are important to prevent complications. Bartonella henselae is difficult to culture, and culture is not routinely recommended. Clinical, serological, radiological, and pathological findings are used for the diagnosis of CSD. Herein we present a case of systemic CSD presenting with hepatic mass in an immunocompetent child. The differential diagnosis is made by serological and pathological evidence. He was successfully treated with gentamicin (7.5 mg/kg) and rifampin (15 mg/kg) for six weeks.
format Article
id doaj-art-caf18ca14a094c24bcabe235d8799171
institution Kabale University
issn 2090-6803
2090-6811
language English
publishDate 2014-01-01
publisher Wiley
record_format Article
series Case Reports in Pediatrics
spelling doaj-art-caf18ca14a094c24bcabe235d87991712025-02-03T07:25:18ZengWileyCase Reports in Pediatrics2090-68032090-68112014-01-01201410.1155/2014/397437397437Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological EvidenceSerkan Atıcı0Eda Kepenekli Kadayıfcı1Ayşe Karaaslan2Muhammed Hasan Toper3Cigdem Ataizi Celikel4Ahmet Soysal5Mustafa Bakır6Department of Pediatrics and Division of Pediatric Infectious Diseases, Marmara University Medical Faculty, Pendik Training and Research Hospital, Fevzi Cakmak Mah. Mimar Sinan Cad., Ust Kaynarca, Pendik, 34899 Istanbul, TurkeyDepartment of Pediatrics and Division of Pediatric Infectious Diseases, Marmara University Medical Faculty, Pendik Training and Research Hospital, Fevzi Cakmak Mah. Mimar Sinan Cad., Ust Kaynarca, Pendik, 34899 Istanbul, TurkeyDepartment of Pediatrics and Division of Pediatric Infectious Diseases, Marmara University Medical Faculty, Pendik Training and Research Hospital, Fevzi Cakmak Mah. Mimar Sinan Cad., Ust Kaynarca, Pendik, 34899 Istanbul, TurkeyDepartment of Pathology, Marmara University Medical Faculty, Pendik Training and Research Hospital, Fevzi Cakmak Mah. Mimar Sinan Cad., Ust Kaynarca, Pendik, 34899 Istanbul, TurkeyDepartment of Pathology, Marmara University Medical Faculty, Pendik Training and Research Hospital, Fevzi Cakmak Mah. Mimar Sinan Cad., Ust Kaynarca, Pendik, 34899 Istanbul, TurkeyDepartment of Pediatrics and Division of Pediatric Infectious Diseases, Marmara University Medical Faculty, Pendik Training and Research Hospital, Fevzi Cakmak Mah. Mimar Sinan Cad., Ust Kaynarca, Pendik, 34899 Istanbul, TurkeyDepartment of Pediatrics and Division of Pediatric Infectious Diseases, Marmara University Medical Faculty, Pendik Training and Research Hospital, Fevzi Cakmak Mah. Mimar Sinan Cad., Ust Kaynarca, Pendik, 34899 Istanbul, TurkeyTypical cat-scratch disease (CSD) is characterized by local lymphadenopathy following the scratch or bite from a cat or kitten. An atypical presentation which includes liver and/or spleen lesions is rarely reported in an immunocompetent child. Systemic CSD may mimic more serious disorders like malignancy or tuberculosis. Although a diagnosis is difficult to establish in systemic CSD, an early diagnosis and an appropriate treatment are important to prevent complications. Bartonella henselae is difficult to culture, and culture is not routinely recommended. Clinical, serological, radiological, and pathological findings are used for the diagnosis of CSD. Herein we present a case of systemic CSD presenting with hepatic mass in an immunocompetent child. The differential diagnosis is made by serological and pathological evidence. He was successfully treated with gentamicin (7.5 mg/kg) and rifampin (15 mg/kg) for six weeks.http://dx.doi.org/10.1155/2014/397437
spellingShingle Serkan Atıcı
Eda Kepenekli Kadayıfcı
Ayşe Karaaslan
Muhammed Hasan Toper
Cigdem Ataizi Celikel
Ahmet Soysal
Mustafa Bakır
Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological Evidence
Case Reports in Pediatrics
title Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological Evidence
title_full Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological Evidence
title_fullStr Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological Evidence
title_full_unstemmed Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological Evidence
title_short Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological Evidence
title_sort atypical presentation of cat scratch disease in an immunocompetent child with serological and pathological evidence
url http://dx.doi.org/10.1155/2014/397437
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AT muhammedhasantoper atypicalpresentationofcatscratchdiseaseinanimmunocompetentchildwithserologicalandpathologicalevidence
AT cigdemataizicelikel atypicalpresentationofcatscratchdiseaseinanimmunocompetentchildwithserologicalandpathologicalevidence
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