Roles of ACSL4/GPX4 and FSP1 in oxalate-induced acute kidney injury

Abstract Ferroptosis has emerged as a crucial driver of injury in various organs, including acute kidney injury (AKI). However, the regulatory roles and underlying mechanisms of key genes involved in ferroptosis during oxalate-induced AKI are not fully understood. In this study, we conducted single-...

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Bibliographic Details
Main Authors: Keng Ye, Ruilong Lan, Zhimin Chen, Kunmei Lai, Yankun Song, Guoping Li, Huabin Ma, Hong Chen, Yanfang Xu
Format: Article
Language:English
Published: Nature Publishing Group 2025-06-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-025-02557-y
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