IMMUNOLOGICAL FACTOR OF INFERTILITY IN MEN OF THE KEMEROVO REGION

The immunological factor is one of the causes of male infertility. If there is a significant amount of sperm in the ejaculate that is sensitive to antisperm antibodies (ASAT), the ability to fertilize may be impaired. Antibodies directed against sperm components have a negative effect on various pro...

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Main Authors: Алексей Андреевич Шмелев, Алексей Геннадьевич Тришкин, Антон Игоревич Лесников, Лилия Владиславовна Курганова, Алексей Дмитриевич Бушмакин, Алексей Сергеевич Ильин
Format: Article
Language:Russian
Published: The Publishing House Medicine and Enlightenment 2024-06-01
Series:Медицина в Кузбассе
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Online Access:https://mednauki.ru/index.php/MK/article/view/1096
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author Алексей Андреевич Шмелев
Алексей Геннадьевич Тришкин
Антон Игоревич Лесников
Лилия Владиславовна Курганова
Алексей Дмитриевич Бушмакин
Алексей Сергеевич Ильин
author_facet Алексей Андреевич Шмелев
Алексей Геннадьевич Тришкин
Антон Игоревич Лесников
Лилия Владиславовна Курганова
Алексей Дмитриевич Бушмакин
Алексей Сергеевич Ильин
author_sort Алексей Андреевич Шмелев
collection DOAJ
description The immunological factor is one of the causes of male infertility. If there is a significant amount of sperm in the ejaculate that is sensitive to antisperm antibodies (ASAT), the ability to fertilize may be impaired. Antibodies directed against sperm components have a negative effect on various processes before and after fertilization. Objective – to identify the prevalence of the immunological factor in men of the Kemerovo region. Compare the spermogram indicators in men with different indicators of the MAR test. Results. It was found out that out of 1827 men with infertility, a positive MAR test was detected in 116, which was 6.35 % of the sample. The negative effect of ASAT on concentration and progressive mobility was demonstrated in the comparison group between a high (90-100 %) and normal (less than 40 %) MAR test index. Conclusion. The prevalence of the immunological factor of infertility in Kuzbass men has been revealed. A difference was found between the indicators of concentration and progressive motility of spermatozoa in the groups with normal and high values of the MAR test.
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institution Kabale University
issn 1819-0901
2588-0411
language Russian
publishDate 2024-06-01
publisher The Publishing House Medicine and Enlightenment
record_format Article
series Медицина в Кузбассе
spelling doaj-art-caeab50829ac453b8353da4de47bad472025-08-20T03:38:49ZrusThe Publishing House Medicine and EnlightenmentМедицина в Кузбассе1819-09012588-04112024-06-012326871939IMMUNOLOGICAL FACTOR OF INFERTILITY IN MEN OF THE KEMEROVO REGIONАлексей Андреевич Шмелев0Алексей Геннадьевич Тришкин1Антон Игоревич Лесников2Лилия Владиславовна Курганова3Алексей Дмитриевич Бушмакин4Алексей Сергеевич Ильин5ФГБОУ ВО КемГУ; ЦОЗСР «Красная Горка», г. КемеровоФГБОУ ВО КемГУ; ЦОЗСР «Красная Горка», г. КемеровоФГБОУ ВО КемГУ; ЦОЗСР «Красная Горка», г. КемеровоФГБОУ ВО КемГУ; ЦОЗСР «Красная Горка», г. КемеровоФГБОУ ВО КемГУ; ЦОЗСР «Красная Горка», г. КемеровоЦОЗСР «Красная Горка», г. КемеровоThe immunological factor is one of the causes of male infertility. If there is a significant amount of sperm in the ejaculate that is sensitive to antisperm antibodies (ASAT), the ability to fertilize may be impaired. Antibodies directed against sperm components have a negative effect on various processes before and after fertilization. Objective – to identify the prevalence of the immunological factor in men of the Kemerovo region. Compare the spermogram indicators in men with different indicators of the MAR test. Results. It was found out that out of 1827 men with infertility, a positive MAR test was detected in 116, which was 6.35 % of the sample. The negative effect of ASAT on concentration and progressive mobility was demonstrated in the comparison group between a high (90-100 %) and normal (less than 40 %) MAR test index. Conclusion. The prevalence of the immunological factor of infertility in Kuzbass men has been revealed. A difference was found between the indicators of concentration and progressive motility of spermatozoa in the groups with normal and high values of the MAR test.https://mednauki.ru/index.php/MK/article/view/1096мужское бесплодиеиммунологический факторпоказатели спермограммыантиспермальные антителаmar-тест
spellingShingle Алексей Андреевич Шмелев
Алексей Геннадьевич Тришкин
Антон Игоревич Лесников
Лилия Владиславовна Курганова
Алексей Дмитриевич Бушмакин
Алексей Сергеевич Ильин
IMMUNOLOGICAL FACTOR OF INFERTILITY IN MEN OF THE KEMEROVO REGION
Медицина в Кузбассе
мужское бесплодие
иммунологический фактор
показатели спермограммы
антиспермальные антитела
mar-тест
title IMMUNOLOGICAL FACTOR OF INFERTILITY IN MEN OF THE KEMEROVO REGION
title_full IMMUNOLOGICAL FACTOR OF INFERTILITY IN MEN OF THE KEMEROVO REGION
title_fullStr IMMUNOLOGICAL FACTOR OF INFERTILITY IN MEN OF THE KEMEROVO REGION
title_full_unstemmed IMMUNOLOGICAL FACTOR OF INFERTILITY IN MEN OF THE KEMEROVO REGION
title_short IMMUNOLOGICAL FACTOR OF INFERTILITY IN MEN OF THE KEMEROVO REGION
title_sort immunological factor of infertility in men of the kemerovo region
topic мужское бесплодие
иммунологический фактор
показатели спермограммы
антиспермальные антитела
mar-тест
url https://mednauki.ru/index.php/MK/article/view/1096
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