A variant of idiopathic epilepsy: Clinical note

The paper describes a clinical case of idiopathic generalized epilepsy with a variable phenotype, a similar type of epileptiform activity in the second stage of sleep, and a similar genotype in siblings. The onset of seizures was observed after closed brain injury in both cases. The sister had myocl...

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Bibliographic Details
Main Authors: V. A. Karlov, S. N. Illarioshkin, G. A. Kovalenko, N. Yu. Abramycheva
Format: Article
Language:Russian
Published: IMA-PRESS LLC 2015-03-01
Series:Неврология, нейропсихиатрия, психосоматика
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Online Access:https://nnp.ima-press.net/nnp/article/view/477
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Summary:The paper describes a clinical case of idiopathic generalized epilepsy with a variable phenotype, a similar type of epileptiform activity in the second stage of sleep, and a similar genotype in siblings. The onset of seizures was observed after closed brain injury in both cases. The sister had myoclonic seizures and her brother had generalized convulsive seizures late in the evening. Idiopathic generalized epilepsy with generalized convulsive seizures appears as generalized tonic-clonic seizures on awakening. But in a number of cases, these seizures may occur when going to sleep. The brother has supposedly idiopathic generalized epilepsy with generalized tonicclonic seizures and his sister has juvenile myoclonic epilepsy, as indicated by her age, hereditary predisposition, phenobarbital-provoked seizures (the latter are also observed in his brother), an electrographic pattern, and the efficacy of Keppra and Topamax.
ISSN:2074-2711
2310-1342