Novel, nanomagnetic and recoverable copper(0)-catalyst in one-pot access to 1,4-disubstituted 1,2,3-triazoles and 5-substituted 1H-tetrazoles in water

A novel Fe3O4@SiO2-Pr-2-Py-Cu(0) complex was produced as a heterogeneous magnetic nanocatalyst and characterized by employing several spectroscopic methods such as XRD, FT-IR, BET, VSM, FE-SEM, ICP, TGA, EDX, mapping, and UV-Vis spectroscopy. The catalytic performance of this novel catalyst was exam...

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Main Authors: Mohammad Amiri, Nastaran Bagherzadeh, Ali Reza Sardarian
Format: Article
Language:English
Published: The Royal Society 2025-02-01
Series:Royal Society Open Science
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Online Access:https://royalsocietypublishing.org/doi/10.1098/rsos.241322
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author Mohammad Amiri
Nastaran Bagherzadeh
Ali Reza Sardarian
author_facet Mohammad Amiri
Nastaran Bagherzadeh
Ali Reza Sardarian
author_sort Mohammad Amiri
collection DOAJ
description A novel Fe3O4@SiO2-Pr-2-Py-Cu(0) complex was produced as a heterogeneous magnetic nanocatalyst and characterized by employing several spectroscopic methods such as XRD, FT-IR, BET, VSM, FE-SEM, ICP, TGA, EDX, mapping, and UV-Vis spectroscopy. The catalytic performance of this novel catalyst was examined for efficient access to diverse 1,4-disubstituted-1,2,3-triazoles via eco-friendly one-pot three-component reactions of sodium azide, various terminal alkynes, and benzyl, allyl, ester, or alkyl halide in aqueous media and mild conditions. In addition, catalyst activity to study the generality and scope of the reaction in the library preparation of 5-substituted 1H-tetrazoles with a variety of electron-withdrawing and electron-donating groups was used through a one-pot reaction of hydroxylamine hydrochloride, diverse aldehydes and sodium azide in water. Catalyst recyclability results showed that it could operate up to eight consecutive runs without a significant reduction in the reaction efficiency. This green strategy assigns substantial advantages such as efficient and environmentally benign procedures, chemical waste minimization, stability and cost-effectiveness, short reaction time, wide-ranging substrate, an excellent yield of desired products and recoverable and reusable nanomagnetic catalysts.
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spelling doaj-art-cae5baeb2df5430d8af70adb2cb8f33c2025-08-20T03:02:06ZengThe Royal SocietyRoyal Society Open Science2054-57032025-02-0112210.1098/rsos.241322Novel, nanomagnetic and recoverable copper(0)-catalyst in one-pot access to 1,4-disubstituted 1,2,3-triazoles and 5-substituted 1H-tetrazoles in waterMohammad Amiri0Nastaran Bagherzadeh1Ali Reza Sardarian2Chemistry Department, College of Science, Shiraz University, Shiraz, Fars, IranChemistry Department, College of Science, Shiraz University, Shiraz, Fars, IranChemistry Department, College of Science, Shiraz University, Shiraz, Fars, IranA novel Fe3O4@SiO2-Pr-2-Py-Cu(0) complex was produced as a heterogeneous magnetic nanocatalyst and characterized by employing several spectroscopic methods such as XRD, FT-IR, BET, VSM, FE-SEM, ICP, TGA, EDX, mapping, and UV-Vis spectroscopy. The catalytic performance of this novel catalyst was examined for efficient access to diverse 1,4-disubstituted-1,2,3-triazoles via eco-friendly one-pot three-component reactions of sodium azide, various terminal alkynes, and benzyl, allyl, ester, or alkyl halide in aqueous media and mild conditions. In addition, catalyst activity to study the generality and scope of the reaction in the library preparation of 5-substituted 1H-tetrazoles with a variety of electron-withdrawing and electron-donating groups was used through a one-pot reaction of hydroxylamine hydrochloride, diverse aldehydes and sodium azide in water. Catalyst recyclability results showed that it could operate up to eight consecutive runs without a significant reduction in the reaction efficiency. This green strategy assigns substantial advantages such as efficient and environmentally benign procedures, chemical waste minimization, stability and cost-effectiveness, short reaction time, wide-ranging substrate, an excellent yield of desired products and recoverable and reusable nanomagnetic catalysts.https://royalsocietypublishing.org/doi/10.1098/rsos.241322aqueous mediaheterogeneous nanocatalyst Cu(0)1,4-disubstituted-1,2,3-triazoles5-substituted 1H-tetrazoles
spellingShingle Mohammad Amiri
Nastaran Bagherzadeh
Ali Reza Sardarian
Novel, nanomagnetic and recoverable copper(0)-catalyst in one-pot access to 1,4-disubstituted 1,2,3-triazoles and 5-substituted 1H-tetrazoles in water
Royal Society Open Science
aqueous media
heterogeneous nanocatalyst Cu(0)
1,4-disubstituted-1,2,3-triazoles
5-substituted 1H-tetrazoles
title Novel, nanomagnetic and recoverable copper(0)-catalyst in one-pot access to 1,4-disubstituted 1,2,3-triazoles and 5-substituted 1H-tetrazoles in water
title_full Novel, nanomagnetic and recoverable copper(0)-catalyst in one-pot access to 1,4-disubstituted 1,2,3-triazoles and 5-substituted 1H-tetrazoles in water
title_fullStr Novel, nanomagnetic and recoverable copper(0)-catalyst in one-pot access to 1,4-disubstituted 1,2,3-triazoles and 5-substituted 1H-tetrazoles in water
title_full_unstemmed Novel, nanomagnetic and recoverable copper(0)-catalyst in one-pot access to 1,4-disubstituted 1,2,3-triazoles and 5-substituted 1H-tetrazoles in water
title_short Novel, nanomagnetic and recoverable copper(0)-catalyst in one-pot access to 1,4-disubstituted 1,2,3-triazoles and 5-substituted 1H-tetrazoles in water
title_sort novel nanomagnetic and recoverable copper 0 catalyst in one pot access to 1 4 disubstituted 1 2 3 triazoles and 5 substituted 1h tetrazoles in water
topic aqueous media
heterogeneous nanocatalyst Cu(0)
1,4-disubstituted-1,2,3-triazoles
5-substituted 1H-tetrazoles
url https://royalsocietypublishing.org/doi/10.1098/rsos.241322
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AT nastaranbagherzadeh novelnanomagneticandrecoverablecopper0catalystinonepotaccessto14disubstituted123triazolesand5substituted1htetrazolesinwater
AT alirezasardarian novelnanomagneticandrecoverablecopper0catalystinonepotaccessto14disubstituted123triazolesand5substituted1htetrazolesinwater